Cell-cell communication is pivotal to guide embryo development, as well as to maintain adult
tissues homeostasis and control immune response. Among extracellular factors responsible …

Semaphorins are extracellular signaling proteins that are essential for the development and
maintenance of many organs and tissues. The more than 20-member semaphorin protein …

Semaphorins are membrane-bound or diffusible factors that regulate key cellular functions
and are involved in cell–cell communication. Most of the effects of semaphorins are …

Semaphorins constitute a large family of membrane-bound and secreted proteins that
provide guidance cues for axon pathfinding and cell migration. Although initially discovered …

The semaphorins constitute a large family of molecular signals with regulatory functions in
neuronal development, angiogenesis, cancer progression and immune responses …

Semaphorins are a large family of developmental regulatory signals, characterized by
aberrant expression in human cancers. These molecules crucially control cell-cell …

Semaphorins are secreted and membrane-associated proteins that regulate many different
developmental processes, including neural circuit assembly, bone formation and …

Semaphorins were originally identified as axon guidance factors involved in the
development of the neuronal system. However, accumulating evidence indicates that …

The semaphorin family is a large group of proteins controlling cell migration and axonal
growth cone guidance. These proteins are bi-functional signals capable of growth promotion …

The inflammatory and immune response elicited by the growth of cancer cells is a major
element conditioning the tumor microenvironment, impinging on disease progression and …