Mass spectrometry strategies in metabolomics

Z Lei, DV Huhman, LW Sumner - Journal of Biological Chemistry, 2011 - ASBMB
MS has evolved as a critical component in metabolomics, which seeks to answer biological
questions through large-scale qualitative and quantitative analyses of the metabolome. MS …

Current challenges and recent developments in mass spectrometry–based metabolomics

SL Collins, I Koo, JM Peters, PB Smith… - Annual review of …, 2021 - annualreviews.org
High-resolution mass spectrometry (MS) has advanced the study of metabolism in living
systems by allowing many metabolites to be measured in a single experiment. Although …

Overview of mass spectrometry-based metabolomics: opportunities and challenges

GAN Gowda, D Djukovic - Mass Spectrometry in Metabolomics: Methods …, 2014 - Springer
The field of metabolomics has witnessed an exponential growth in the last decade driven by
important applications spanning a wide range of areas in the basic and life sciences and …

Advances in mass spectrometry-based metabolomics for investigation of metabolites

JL Ren, AH Zhang, L Kong, XJ Wang - RSC advances, 2018 - pubs.rsc.org
Metabolomics is the systematic study of all the metabolites present within a biological
system, which consists of a mass of molecules, having a variety of physical and chemical …

Mass spectrometry‐based metabolomics: applications to biomarker and metabolic pathway research

A Zhang, H Sun, G Yan, P Wang… - Biomedical …, 2016 - Wiley Online Library
Mass spectrometry‐based metabolomics has become increasingly popular in molecular
medicine. High‐definition mass spectrometry (MS), coupled with pattern recognition …

Mass spectrometry based environmental metabolomics: a primer and review

MR Viant, U Sommer - Metabolomics, 2013 - Springer
Environmental metabolomics can be described as the study of the interactions of living
organisms with their natural environments at the metabolic level. Until recently, nuclear …

Eight key rules for successful data‐dependent acquisition in mass spectrometry‐based metabolomics

E Defossez, J Bourquin, S von Reuss… - Mass Spectrometry …, 2023 - Wiley Online Library
In recent years, metabolomics has emerged as a pivotal approach for the holistic analysis of
metabolites in biological systems. The rapid progress in analytical equipment, coupled to the …

Mass spectrometry-based metabolomics in health and medical science: A systematic review

X Zhang, Q Li, J Dou - RSC advances, 2020 - pubs.rsc.org
Metabolomics is the study of the investigation of small molecules derived from cellular and
organism metabolism, which reflects the outcomes of the complex network of biochemical …

Mass spectrometry in metabolome analysis

SG Villas‐Bôas, S Mas, M Åkesson… - Mass spectrometry …, 2005 - Wiley Online Library
In the post‐genomic era, increasing efforts have been made to describe the relationship
between the genome and the phenotype in cells and organisms. It has become clear that …

Metabolomics technologies and metabolite identification

S Moco, J Vervoort, RJ Bino, RCH De Vos… - TrAC Trends in Analytical …, 2007 - Elsevier
Metabolomics studies rely on the analysis of the multitude of small molecules (metabolites)
present in a biological system. Most commonly, metabolomics is heavily supported by mass …