The inflammatory pathogenesis of colorectal cancer
M Schmitt, FR Greten - Nature Reviews Immunology, 2021 - nature.com
The mutational landscape of colorectal cancer (CRC) does not enable predictions to be
made about the survival of patients or their response to therapy. Instead, studying the …
made about the survival of patients or their response to therapy. Instead, studying the …
Emerging cytokine networks in colorectal cancer
Cytokine networks are crucial aspects of tumour immunology, particularly for colorectal
cancer (CRC), in which inflammation and antitumour immunity are key determinants of …
cancer (CRC), in which inflammation and antitumour immunity are key determinants of …
Immune cells: plastic players along colorectal cancer progression
G Di Caro, F Marchesi, L Laghi… - Journal of cellular and …, 2013 - Wiley Online Library
Inflammatory cells are involved in tumour initiation and progression. In parallel, the adaptive
immune response plays a key role in fighting tumour growth and dissemination. The double …
immune response plays a key role in fighting tumour growth and dissemination. The double …
Multiregion single‐cell sequencing reveals the transcriptional landscape of the immune microenvironment of colorectal cancer
W Wang, Y Zhong, Z Zhuang, J Xie, Y Lu… - Clinical and …, 2021 - Wiley Online Library
The tumor microenvironment is a complex ecosystem formed by distinct and interacting cell
populations, and its composition is related to cancer prognosis and response to clinical …
populations, and its composition is related to cancer prognosis and response to clinical …
Cytokine‐and chemokine‐induced inflammatory colorectal tumor microenvironment: Emerging avenue for targeted therapy
Colorectal cancer (CRC) is a predominant life‐threatening cancer, with liver and peritoneal
metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor …
metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor …
[HTML][HTML] The cytokine network in colorectal cancer: Implications for new treatment strategies
H Braumüller, B Mauerer, J Andris, C Berlin, T Wieder… - Cells, 2022 - mdpi.com
Colorectal cancer (CRC) is one of the most frequent tumor entities worldwide with only
limited therapeutic options. CRC is not only a genetic disease with several mutations in …
limited therapeutic options. CRC is not only a genetic disease with several mutations in …
[HTML][HTML] Prognostic value of innate and adaptive immunity in colorectal cancer
Colorectal cancer (CRC) remains one of the major public health problems throughout the
world. Originally depicted as a multi-step dynamical disease, CRC develops slowly over …
world. Originally depicted as a multi-step dynamical disease, CRC develops slowly over …
Inflammation and colorectal cancer
AG Long, ET Lundsmith, KE Hamilton - Current colorectal cancer reports, 2017 - Springer
Abstract Purpose of Review Colorectal cancer (CRC) is the fourth most common cancer in
both men and women in the USA, resulting in over 55,000 deaths annually. Environmental …
both men and women in the USA, resulting in over 55,000 deaths annually. Environmental …
Microbiome, inflammation and colorectal cancer
J Chen, E Pitmon, K Wang - Seminars in immunology, 2017 - Elsevier
Chronic inflammation is linked to the development of multiple cancers, including those of the
colon. Inflammation in the gut induces carcinogenic mutagenesis and promotes colorectal …
colon. Inflammation in the gut induces carcinogenic mutagenesis and promotes colorectal …
[HTML][HTML] Immune system, microbiota, and microbial metabolites: the unresolved triad in colorectal cancer microenvironment
M Hanus, D Parada-Venegas, G Landskron… - Frontiers in …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common cancers worldwide. As with other
cancers, CRC is a multifactorial disease due to the combined effect of genetic and …
cancers, CRC is a multifactorial disease due to the combined effect of genetic and …