One of the key aspects of coping efficiently with complex pathological conditions is
delivering the desired therapeutic compounds with precision in both space and time …

Nanosystems with unique physical and biological properties have been extensively
explored for cancer targeted intracellular delivery of small-molecular chemotherapeutic …

New biopharmaceutical molecules, potentially able to provide more personalized and
effective treatments, are being identified through the advent of advanced synthetic biology …

Tumor cell nucleus-targeted delivery of antitumor agents is of great interest in cancer
therapy, since the nucleus is one of the most frequent targets of drug action. Here we report …

Nucleus, as the machinery for genome transcription, play prominent roles to support the
fundamental cellular functions, the destruction of any of these specific parts would …

Nanomedicine 2.0 refers to the next generation of nanotechnology-based medical therapies
and diagnostic tools. This field focuses on the development of more sophisticated and …

Targeted drug delivery is critical for improving the therapeutic benefits of anticancer drugs.
The active delivery strategy increases the bioavailability of drugs not only to the diseased …

Drug delivery systems largely contribute to cancer therapy in terms of tumor targeting and
controlled release of cargo molecules. While targeting of tumor “tissue” has been achieved …

The nucleus is ultimately the final target for many therapeutics treating various disorders
including cancers, heart dysfunction and brain disorders. Owing to their specialized cell …

The nucleus is the final target of many first‐line chemotherapeutics, but the need to
overcome multiple physiological barriers imposes conflicting requirements for size and …