Breast cancer is the disease with the highest impact on global health, being metastasis the
main cause of death. To metastasize, carcinoma cells must reactivate a latent program …

Abstract Glypican-4 (GPC-4) is a heparan sulphate glycoprotein, associated with cell
membrane via a Glycosyl phosphatidyl (GPI)-anchor. It is involved in cell migration, cell …

Abstract Glypican-3 (GPC3) is a proteoglycan involved in migration, proliferation and cell
survival modulation in several tissues. There are many reports demonstrating a …

Background The Glycine N-acyltransferase (GLYAT) gene encodes a protein that catalyzes
the transfer of acyl groups from acyl CoA to glycine, resulting in acyl glycine and coenzyme …

Purpose Treatment of metastatic breast cancer patients is challenging and remains a major
underlying cause of female mortality. Understanding molecular alterations in tumor …

Abstract Glypican-3 (GPC3) is a proteoglycan involved in proliferation and cell survival.
Several reports demonstrated that GPC3 is downregulated in some tumors, such as breast …

Abstract Glypican-3 (GPC3), a proteoglycan bound to the cell membrane through a GPI
anchor, is widely expressed in the embryo but down regulated in most adult tissues, with …

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is a
major cause of cancer-related death worldwide. Previously, we demonstrated that glypican …

Abstract Glypican-3 (gpc3) is the gene responsible for Simpson-Golabi-Behmel overgrowth
syndrome. Previously, we have shown that GPC3 is overexpressed in hepatocellular …

Abstract Glypican-3 (GPC3), a membrane-associated heparan sulfate proteoglycan, is
frequently upregulated in hepatocellular carcinoma (HCC). However, how GPC3 contributes …