Prospective cohort study using the breast cancer spheroid model as a predictor for response to neoadjuvant therapy–the SpheroNEO study

K Halfter, N Ditsch, HC Kolberg, H Fischer… - BMC cancer, 2015 - Springer
Background Aim of this prospective study was to predict response to neoadjuvant therapy in
breast cancer patients using an in vitro breast cancer spheroid model. Methods Three …

Tumor sphericity predicts response in neoadjuvant chemotherapy for invasive breast cancer

W Li, DC Newitt, B La Yun, EF Jones, V Arasu… - Tomography, 2020 - mdpi.com
This retrospective study examined magnetic resonance imaging (MRI)–derived tumor
sphericity (SPH) as a quantitative measure of breast tumor morphology, and investigated the …

[HTML][HTML] Mammographic density to predict response to neoadjuvant systemic breast cancer therapy

S Di Cosimo, C Depretto, R Miceli, P Baili… - Journal of Cancer …, 2022 - Springer
Background Mammographic density (MD) is a risk factor for breast cancer (BC)
development, and recurrence. However, its predictive value has been less studied. Herein …

Novel computational biology modeling system can accurately forecast response to neoadjuvant therapy in early breast cancer

JR Peterson, JA Cole, JR Pfeiffer, GH Norris… - Breast Cancer …, 2023 - Springer
Background Generalizable population-based studies are unable to account for individual
tumor heterogeneity that contributes to variability in a patient's response to physician-chosen …

A nomogram based on clinicopathological features and serological indicators predicting breast pathologic complete response of neoadjuvant chemotherapy in breast …

Y Li, J Zhang, B Wang, H Zhang, J He, K Wang - Scientific reports, 2021 - nature.com
A single tumor marker is not enough to predict the breast pathologic complete response
(bpCR) after neoadjuvant chemotherapy (NAC) in breast cancer patients. We aimed to …

Construction of nomograms for predicting pathological complete response and tumor shrinkage size in breast cancer

S Yan, W Wang, B Zhu, X Pan, X Wu… - Cancer Management and …, 2020 - Taylor & Francis
Purpose Pathological complete response (pCR) is the goal of neoadjuvant chemotherapy
(NAC) for the HER2-positive and triple-negative subtypes of breast cancer and is related to …

Accuracy of digital mammography, ultrasound and MRI in predicting the pathological complete response and residual tumor size of breast cancer after completion of …

R Sudhir, VC Koppula, TS Rao… - Indian Journal of …, 2022 - journals.lww.com
Background: Neoadjuvant chemotherapy (NACT) is the standard of care for the treatment of
locally advanced or non-metastatic breast cancer, which may increase the chances of breast …

[HTML][HTML] Nomogram predicting clinical outcomes in breast cancer patients treated with neoadjuvant chemotherapy

B Keam, SA Im, S Park, BH Nam, SW Han… - Journal of cancer …, 2011 - Springer
Purpose The aim of this study was to combine clinical pathologic variables that are
associated with pathologic completer response (pCR) and relapse-free survival (RFS) after …

Development of a nomogram for predicting pathological complete response in luminal breast cancer patients following neoadjuvant chemotherapy

G Garufi, L Carbognin, I Sperduti… - Therapeutic …, 2023 - journals.sagepub.com
Background: Given the low chance of response to neoadjuvant chemotherapy (NACT) in
luminal breast cancer (LBC), the identification of predictive factors of pathological complete …

Evaluation of the pathological response and prognosis following neoadjuvant chemotherapy in molecular subtypes of breast cancer

Y Zhao, X Dong, R Li, X Ma, J Song, Y Li… - OncoTargets and …, 2015 - Taylor & Francis
Background The pathological complete response of neoadjuvant chemotherapy for breast
cancer correlates with the prognosis for survival. Tumors may have different prognoses …