Mechanistic insight of diabetic nephropathy and its pharmacotherapeutic targets: an update

N Bhattacharjee, S Barma, N Konwar… - European journal of …, 2016 - Elsevier
Diabetic nephropathy (DN), a chronic complication of diabetes, is charecterized by
glomerular hypertrophy, proteinuria, decreased glomerular filtration, and renal fibrosis …

Pathophysiology of diabetic nephropathy: involvement of multifaceted signalling mechanism

P Balakumar, MK Arora, J Reddy… - Journal of …, 2009 - journals.lww.com
Diabetic nephropathy is a major cause of end-stage renal failure and the mortality rate due
to this disease is continuously progressing worldwide. The multifaceted signalling …

Research progress in signalling pathway in diabetic nephropathy

WJ Ni, LQ Tang, W Wei - Diabetes/metabolism research and …, 2015 - Wiley Online Library
Diabetic nephropathy, a lethal diabetic complication, is a leading cause of end‐stage renal
disease, which is pathologically characterized by thickened tubular basal and glomerular …

Recent advances in understanding the biochemical and molecular mechanism of diabetic nephropathy

YM Sun, Y Su, J Li, LF Wang - Biochemical and biophysical research …, 2013 - Elsevier
Diabetic nephropathy (DN) is a chronic disease characterized by proteinuria, glomerular
hypertrophy, decreased glomerular filtration and renal fibrosis with loss of renal function. DN …

Molecular mechanisms of diabetic nephropathy and its therapeutic intervention

S Yamagishi, K Fukami, S Ueda… - Current drug targets, 2007 - ingentaconnect.com
Diabetic nephropathy is a leading cause of end-stage renal failure, which could account for
disabilities and high mortality rates in patients with diabetes. Diabetic nephropathy seems to …

Recent advances in pharmacotherapy for diabetic nephropathy: current perspectives and future directions

P Balakumar, MK Arora, SS Ganti, J Reddy… - Pharmacological …, 2009 - Elsevier
Chronic diabetes mellitus is associated with various complications such as retinopathy,
neuropathy, nephropathy, cardiomyopathy, vasculopathy, dermatopathy and …

Oxidative stress: meeting multiple targets in pathogenesis of diabetic nephropathy

M Kumar Arora, U Kumar Singh - Current drug targets, 2014 - ingentaconnect.com
Excessive production of reactive oxygen species is an important mechanism underlying the
pathogenesis of diabetes associated macrovascular and microvascular complications …

What's new in the molecular mechanisms of diabetic kidney disease: recent advances

K Watanabe, E Sato, E Mishima, M Miyazaki… - International journal of …, 2022 - mdpi.com
Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease, including end-
stage kidney disease, and increases the risk of cardiovascular mortality. Although the …

Oxidative stress in diabetic nephropathy

N Kashihara, Y Haruna, VK Kondeti… - Current medicinal …, 2010 - ingentaconnect.com
Diabetic nephropathy is a leading cause of end-stage renal failure worldwide. Its
morphologic characteristics include glomerular hypertrophy, basement membrane …

Inflammation and oxidative stress in diabetic nephropathy: new insights on its inhibition as new therapeutic targets

A Mima - Journal of diabetes research, 2013 - Wiley Online Library
Diabetes and insulin resistance can greatly increase microvascular complications of
diabetes including diabetic nephropathy (DN). Hyperglycemic control in diabetes is key to …