Oxidative stress contributes to the pathogenesis of acute lung injury. Protein S-
glutathionylation plays an important role in cellular antioxidant defense. Here we report that …

Fatty acid binding protein 5 (FABP5) is mainly involved in the uptake, transport, and
metabolism of fatty acid in the cytoplasm, and its role in immune cells has been recognized …

Obesity-linked metabolic disease is mechanistically associated with the accumulation of
proinflammatory macrophages in adipose tissue, leading to increased reactive oxygen …

Chronic inflammation in obese adipose tissue is linked to endoplasmic reticulum (ER) stress
and systemic insulin resistance. Targeted deletion of the murine fatty acid binding protein …

Atherosclerosis is a chronic inflammatory vascular disease, and inflammation plays a critical
role in its formation and progression. Elevated serum homocysteine (Hcy) is an independent …

Intake of the micronutrient selenium, which is incorporated into 25 selenoproteins in
humans, has been implicated in affecting risk of colorectal cancer. A genetic variant in the …

Lung ischemia-reperfusion (I/R) injury remains one of the most common complications after
various cardiopulmonary surgeries. The inflammation response triggered by the released …

Rationale: The NF-E2 related factor 2 (Nrf2)–antioxidant response element (ARE) pathway
is essential for protection against oxidative injury and inflammation including hyperoxia …

Fatty acids (FAs) are widely involved in diverse biological functions. In mice with myeloid-
specific deletion of fatty acid-binding protein 5 (FABP5), OVA-induced allergic airway …

Oxidative stress in conjunction with glutathione depletion has been linked with various acute
and chronic degenerative disorders, yet the molecular mechanisms have remained unclear …