[HTML][HTML] SG2NA is a regulator of endoplasmic reticulum (ER) homeostasis as its depletion leads to ER stress

BP Jain, S Pandey, N Saleem, GK Tanti… - Cell Stress and …, 2017 - Elsevier
SG2NA belongs to a three-member striatin subfamily of WD40 repeat superfamily of
proteins. It has multiple protein-protein interaction domains involved in assembling …

Subcellular dynamics of variants of SG2NA in NIH3T3 fibroblasts

P Chauhan, R Gupta, BP Jain, S Pandey… - Cell Biology …, 2020 - Wiley Online Library
Abstract SG2NA, a WD40 repeat protein of the Striatin subfamily, has four splicing and one
messenger RNA edit variants. It is fast emerging as a scaffold for multimeric signaling …

Tissue specific expression of SG2NA is regulated by differential splicing, RNA editing and differential polyadenylation

BP Jain, P Chauhan, GK Tanti, N Singarapu… - Gene, 2015 - Elsevier
SG2NA belongs to a three member Striatin subfamily of WD-40 repeat superfamily. It has
multiple protein–protein interaction domains that are involved in the assembly of supra …

Ectopic expression of 35 kDa and knocking down of 78 kDa SG2NAs induce cytoskeletal reorganization, alter membrane sialylation, and modulate the markers of EMT

R Gupta, G Kumar, BP Jain, S Chandra… - Molecular and Cellular …, 2021 - Springer
SG2NA is a protein of the striatin family that organizes STRIPAK complexes. It has splice
variants expressing differentially in tissues. Its 78 kDa isoform regulates cell cycle, maintains …

GSK3β and ERK regulate the expression of 78 kDa SG2NA and ectopic modulation of its level affects phases of cell cycle

S Pandey, I Talukdar, BP Jain, GK Tanti… - Scientific Reports, 2017 - nature.com
Striatin and SG2NA are essential constituents of the multi-protein STRIPAK assembly
harbouring protein phosphatase PP2A and several kinases. SG2NA has several isoforms …

Molecular modeling and molecular dynamics simulations based structural analysis of the SG2NA protein variants

S Soni, C Tyagi, A Grover, SK Goswami - BMC research Notes, 2014 - Springer
Background SG2NA is a member of the striatin sub-family of WD-40 repeat proteins. Striatin
family members have been associated with diverse physiological functions. SG2NA has also …

WD-40 repeat protein SG2NA has multiple splice variants with tissue restricted and growth responsive properties

M Sanghamitra, I Talukder, N Singarapu, KV Sindhu… - Gene, 2008 - Elsevier
SG2NA is a member of the striatin family of WD-40 repeat proteins with potential scaffolding
functions. It was originally identified as a tumor antigen with increased expression during S …

Stress‐and cell cycle‐associated regulation of RGS2 mRNA levels

JW Zmijewski, L Song, RS Jope - Neuroscience Research …, 2004 - Wiley Online Library
Regulators of G‐protein signaling family members, such as RGS2, are thought to primarily
be involved in regulating the activity of second messenger systems by attenuating …

Cellular stress increases RGS2 mRNA and decreases RGS4 mRNA levels in SH-SY5Y cells

L Song, RS Jope - Neuroscience letters, 2006 - Elsevier
Modulation of the expression of regulator of G-protein signaling (RGS) proteins is a major
mechanism used to modulate their actions. Besides control by second messengers, the …

Mild heat and proteotoxic stress promote unique subcellular trafficking and nucleolar accumulation of RGS6 and other RGS proteins: role of the RGS domain in stress …

TK Chatterjee, RA Fisher - Journal of Biological Chemistry, 2003 - ASBMB
RGS proteins comprise a large family of proteins named for their ability to negatively
regulate heterotrimeric G protein signaling. RGS6 is a member of the R7 subfamily of RGS …