Clinical utility of circulating non-coding RNAs—an update

S Anfossi, A Babayan, K Pantel, GA Calin - Nature reviews Clinical …, 2018 - nature.com
Over the past decade, the amount of research and the number of publications on
associations between circulating small and long non-coding RNAs (ncRNAs) and cancer …

[HTML][HTML] Circulating long non-coding RNAs in cancer: current status and future perspectives

P Qi, X Zhou, X Du - Molecular cancer, 2016 - Springer
Long non-coding RNAs (lncRNAs) comprise a diverse class of RNA transcripts> 200
nucleotides in length with limited protein-coding potential. In addition to their possible role in …

Circulating microRNAs: potential biomarkers for common malignancies

S Khoury, N Tran - Biomarkers in medicine, 2015 - Taylor & Francis
MicroRNAs (miRNAs) belong to a class of small noncoding RNAs (ncRNAs), which regulate
gene expression at the post-transcriptional level. They are approximately 22 nucleotide …

Circulating miRNAs: roles in cancer diagnosis, prognosis and therapy

G Cheng - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) belong to a class of small non-coding RNAs that regulate numerous
biological processes by targeting a broad set of messenger RNAs. Recently, miRNAs have …

[HTML][HTML] Non-coding RNAs in cancer initiation and progression and as novel biomarkers

SP Nana-Sinkam, CM Croce - Molecular oncology, 2011 - Elsevier
Cancer represents a complex group of heterogeneous diseases. While many cancers share
fundamental biological processes (hallmarks of cancer) necessary for their development …

[HTML][HTML] Blood-derived lncRNAs as biomarkers for cancer diagnosis: the Good, the Bad and the Beauty

C Badowski, B He, LX Garmire - NPJ precision oncology, 2022 - nature.com
Cancer ranks as one of the deadliest diseases worldwide. The high mortality rate associated
with cancer is partially due to the lack of reliable early detection methods and/or inaccurate …

Circulating microRNAs: a novel class of biomarkers to diagnose and monitor human cancers

K Zen, CY Zhang - Medicinal research reviews, 2012 - Wiley Online Library
Specific and sensitive non‐invasive biomarkers for the detection of human epithelial
malignancies are urgently required to reduce the worldwide morbidity and mortality caused …

[HTML][HTML] Circulating microRNAs in cancer: origin, function and application

R Ma, T Jiang, X Kang - Journal of experimental & clinical cancer research, 2012 - Springer
MicroRNAs (miRNAs) are a class of small non-coding RNAs that regulate gene expression
at the posttranscriptional level. The dysregulation of miRNAs has been linked to a series of …

miRNAs and long noncoding RNAs as biomarkers in human diseases

K Van Roosbroeck, J Pollet… - Expert review of molecular …, 2013 - Taylor & Francis
Noncoding RNAs (ncRNAs) are transcripts that have no apparent protein-coding capacity;
however, many ncRNAs have been found to play a major biological role in human …

[HTML][HTML] Circulating miRNAs in cancer: from detection to therapy

WT Wang, YQ Chen - Journal of hematology & oncology, 2014 - Springer
Since the discovery of circulating microRNAs (miRNAs) in body fluids, an increasing number
of studies have focused on their potential as non-invasive biomarkers and as therapeutic …