Biosynthesis and synthetic biology of psychoactive natural products
Psychoactive natural products play an integral role in the modern world. The tremendous
structural complexity displayed by such molecules confers diverse biological activities of …
structural complexity displayed by such molecules confers diverse biological activities of …
The biochemistry of phytocannabinoids and metabolic engineering of their production in heterologous systems
K Blatt-Janmaat, Y Qu - International Journal of Molecular Sciences, 2021 - mdpi.com
The medicinal properties of cannabis and the its legal status in several countries and
jurisdictions has spurred the massive growth of the cannabis economy around the globe …
jurisdictions has spurred the massive growth of the cannabis economy around the globe …
[图书][B] Biomimetic organic synthesis
In this exciting 2 volume set, the approach and methodology of bio-inspired synthesis of
complex natural products is laid out, backed by abundant practical examples from the …
complex natural products is laid out, backed by abundant practical examples from the …
High-Throughput, Microarray-Based Synthesis of Natural Product Analogues via in Vitro Metabolic Pathway Construction
The generation of biological diversity by engineering the biosynthetic gene assembly of
metabolic pathway enzymes has led to a wide range of “unnatural” variants of natural …
metabolic pathway enzymes has led to a wide range of “unnatural” variants of natural …
Natural products version 2.0: connecting genes to molecules
CT Walsh, MA Fischbach - Journal of the American Chemical …, 2010 - ACS Publications
Natural products have played a prominent role in the history of organic chemistry, and they
continue to be important as drugs, biological probes, and targets of study for synthetic and …
continue to be important as drugs, biological probes, and targets of study for synthetic and …
Cannabinoids: biosynthesis and biotechnological applications
S Sirikantaramas, F Taura - Cannabis sativa L.-Botany and biotechnology, 2017 - Springer
Cannabinoids are unique terpenophenolic metabolites found only in Cannabis sativa. The
biosynthetic mechanism of these compounds had long been ambiguous since conventional …
biosynthetic mechanism of these compounds had long been ambiguous since conventional …
Combinatorial biosynthesis of 'unnatural'natural products: the polyketide example
CJ Tsoi, C Khosla - Chemistry & Biology, 1995 - Elsevier
Multi-enzyme systems such as those involved in the biosynthesis of polyketides, typically
catalyze several distinct reactions that are combined in different ways to generate diverse …
catalyze several distinct reactions that are combined in different ways to generate diverse …
Biomimetic syntheses of aromatic polyketide metabolites
TM Harris, CM Harris - Pure and Applied Chemistry, 1986 - degruyter.com
HNYYO O1LMe Page 1 Pure & App!. Chem., Vol. 58, No. 2, pp. 283—294, 1986. Printed in
Great Britain. © 1986 IUPAC Biomimetic syntheses of aromatic polyketide metabolites T. M …
Great Britain. © 1986 IUPAC Biomimetic syntheses of aromatic polyketide metabolites T. M …
Polyketide β-branching: diversity, mechanism and selectivity
PD Walker, ANM Weir, CL Willis, MP Crump - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 2008 to August 2020 Polyketides are a family of natural products constructed from
simple building blocks to generate a diverse range of often complex chemical structures with …
simple building blocks to generate a diverse range of often complex chemical structures with …
Isoprenoid-like alkylations in polyketide biosynthesis
CT Calderone - Natural product reports, 2008 - pubs.rsc.org
Polyketides are secondary metabolites biosynthesized by the iterative Claisen condensation
of malonate units. Despite utilizing only a small set of biochemical transformations, the …
of malonate units. Despite utilizing only a small set of biochemical transformations, the …