Correlation between small-cell lung cancer serum protein/peptides determined by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and …

Z Li, J Chen, B Xu, W Zhao, H Zha, Y Han, W Shen… - Clinical Proteomics, 2024 - Springer
Background Currently, no effective measures are available to predict the curative efficacy of
small-cell lung cancer (SCLC) chemotherapy. We expect to develop a method for effectively …

[PDF][PDF] Detection and significance of small-cell lung cancer serum protein markers using MALDI-TOF-MS

Z Li, C Tang, X Li, J Li, W Wang, H Qin, B Xu… - International Journal of …, 2017 - e-century.us
Early diagnosis is vital to improving the survival rate of patients with small-cell lung cancer
(SCLC). Considering recent applications of mass spectrometry (MS) to cancer research, this …

Identification of candidate serum biomarkers for small cell lung cancer by proteomics analysis.

J Shi, J Liu, L Liao, Y Guo, H Wang, W Hu, T Hu - Minerva Medica, 2014 - europepmc.org
Aim Detection of novel tumor biomarker will aid in diagnosis of early-stage small cell lung
cancer (SCLC). The purpose of this study was to identify novel tumor biomarker in serum …

[HTML][HTML] Support vector machines coupled with proteomics approaches for detecting biomarkers predicting chemotherapy resistance in small cell lung cancer

M Han, J Dai, Y Zhang, Q Lin, M Jiang… - Oncology …, 2012 - spandidos-publications.com
The aim of this study was to identify serum protein fingerprints of small cell lung cancer
(SCLC) and potential biomarkers related to chemotherapy resistance of SCLC with surface …

Detection and significance of serum protein markers of small‐cell lung cancer

M Han, Q Liu, J Yu, S Zheng - Journal of clinical laboratory …, 2008 - Wiley Online Library
Currently, no satisfactory biomarkers are available to screen for small‐cell lung cancer
(SCLC). We applied a surface‐enhanced laser desorption/ionization time‐of‐flight mass …

Prediction of outcome of non-small cell lung cancer patients treated with chemotherapy and bortezomib by time-course MALDI-TOF-MS serum peptide profiling

J Voortman, TV Pham, JC Knol, G Giaccone… - Proteome Science, 2009 - Springer
Background Only a minority of patients with advanced non-small cell lung cancer (NSCLC)
benefit from chemotherapy. Serum peptide profiling of NSCLC patients was performed to …

Time-course MALDI-TOF-MS serum peptide profiling of non-small cell lung cancer patients treated with bortezomib, cisplatin and gemcitabine

J Voortman, TV Pham, JC Knol, G Giaccone… - Journal of Clinical …, 2008 - ascopubs.org
8007 Background: A limited number of patients with advanced stage non-small cell lung
cancer (NSCLC) respond to chemotherapy. Serum peptide profiling of patients treated with …

Use of anchorchip-time-of-flight spectrometry technology to screen tumor biomarker proteins in serum for small cell lung cancer

J Du, S Yang, X Lin, L Bu, Y Nan, S Huo, W Shang - Diagnostic Pathology, 2010 - Springer
Background The purpose of this study is to discover potential biomarkers in serum for the
detection of small cell lung cancer (SCLC). Methods 74 serum samples including 30 from …

Identification of novel low molecular weight serum peptidome biomarkers for non‐small cell lung cancer (NSCLC)

J Yang, YC Song, TS Song, XY Hu… - Journal of clinical …, 2012 - Wiley Online Library
Aim To identify discriminating protein patterns in serum samples among non‐small cell lung
cancer (NSCLC), chronic obstructive pulmonary disease (COPD), pneumonia, and healthy …

Response and toxicity prediction by MALDI‐TOF‐MS serum peptide profiling in patients with non‐small cell lung cancer

M Rovithi, JSW Lind, TV Pham… - PROTEOMICS …, 2016 - Wiley Online Library
Purpose We validated a previously reported proteomic signature, associated with treatment
outcome, in an independent cohort of patients with non‐small cell lung cancer (NSCLC). A …