We found that Acinetobacter baumannii contains a pgaABCD locus that encodes proteins
that synthesize cell-associated poly-β-(1-6)-N-acetylglucosamine (PNAG). Both a mutant …

Escherichia coli contains a four-gene operon, pgaABCD, which encodes the proteins
necessary for the synthesis of polymeric N-acetylglucosamine, or PGA. Poly-N-acetyl …

The linear homopolymer poly-β-1, 6-N-acetyl-d-glucosamine (β-1, 6-GlcNAc; PGA) serves
as an adhesin for the maintenance of biofilm structural stability in diverse eubacteria. Its …

The pgaABCD operon of Escherichia coli is required for production of the biofilm adhesin
poly-β-1, 6-N-acetyl-d-glucosamine (PGA). We establish here that NhaR, a DNA-binding …

Acinetobacter baumannii is an emerging cause of nosocomial infections. The isolation of
strains resistant to multiple antibiotics is increasing at alarming rates. Although A. baumannii …

Production of a polysaccharide matrix is a hallmark of bacterial biofilms, but the composition
of matrix polysaccharides and their functions are not widely understood. Previous studies of …

Acinetobacter baumannii has emerged as one of the most common extensive drug-resistant
nosocomial bacterial pathogens. Not only can the bacteria survive in hospital settings for …

Acinetobacter baumannii has emerged as an increasing multidrug-resistant threat in
hospitals and a common opportunistic nosocomial pathogen worldwide. However …

ABSTRACT Polymeric β-1, 6-N-acetyl-d-glucosamine (poly-β-1, 6-GlcNAc) has been
implicated as an Escherichia coli and Staphylococcus epidermidis biofilm adhesin, the …

Acinetobacter baumannii has received much attention in recent years because of its
increasing involvement in a number of severe infections and outbreaks occurring in clinical …