Monte Carlo simulation of gold nanoparticles for X-ray enhancement application
Abstract Background Gold nanoparticles (Au NPs) are regarded as potential agents that
enhance the radiosensitivity of tumor cells for theranostic applications. To elucidate the …
enhance the radiosensitivity of tumor cells for theranostic applications. To elucidate the …
Simulation on the molecular radiosensitization effect of gold nanoparticles in cells irradiated by x-rays
WZ Xie, W Friedland, WB Li, CY Li, U Oeh… - Physics in Medicine …, 2015 - iopscience.iop.org
Abundant studies have focused on the radiosensitization effect of gold nanoparticles (GNPs)
in the cellular environment with x-ray irradiation. To better understand the physical …
in the cellular environment with x-ray irradiation. To better understand the physical …
Intercomparison of dose enhancement ratio and secondary electron spectra for gold nanoparticles irradiated by X-rays calculated using multiple Monte Carlo …
Purpose Targeted radiation therapy has seen an increased interest in the past decade. In
vitro and in vivo experiments showed enhanced radiation doses due to gold nanoparticles …
vitro and in vivo experiments showed enhanced radiation doses due to gold nanoparticles …
[HTML][HTML] Multi-scale Monte Carlo simulations of gold nanoparticle-induced DNA damages for kilovoltage X-ray irradiation in a xenograft mouse model using TOPAS …
Abstract Background Gold nanoparticles (AuNPs) are considered as promising agents to
increase the radiosensitivity of tumor cells. However, the biological mechanisms of radiation …
increase the radiosensitivity of tumor cells. However, the biological mechanisms of radiation …
Monte Carlo simulations of dose enhancement around gold nanoparticles used as x-ray imaging contrast agents and radiosensitizers
WB Li, M Müllner, MB Greiter… - … 2014: Physics of …, 2014 - spiedigitallibrary.org
Gold nanoparticles (GNPs) were demonstrated as X-ray imaging contrast agents and
radiosensitizers in mice. However, the translational medical applications of GNPs in to the …
radiosensitizers in mice. However, the translational medical applications of GNPs in to the …
Computational modeling and clonogenic assay for radioenhancement of gold nanoparticles using 3D live cell images
Radioenhancement of gold nanoparticles (GNPs) has shown great potential for increasing
the therapeutic efficiency of radiotherapy. Here we report on a computational model of …
the therapeutic efficiency of radiotherapy. Here we report on a computational model of …
Microdosimetric-kinetic model for radio-enhancement of gold nanoparticles: Comparison with LEM
Numerous studies have strongly supported the application of gold nanoparticles (GNPs) as
radio-enhanced agents. In our previous study, the local effect model (LEM I) was adopted to …
radio-enhanced agents. In our previous study, the local effect model (LEM I) was adopted to …
Monte Carlo investigation of the effect of gold nanoparticles' distribution on cellular dose enhancement
FS Rasouli, SF Masoudi - Radiation Physics and Chemistry, 2019 - Elsevier
Purpose In recent decades, radiotherapy has became one of the most useful and cost
effective tools in cancer treatment. Having a number of unique characteristics made gold …
effective tools in cancer treatment. Having a number of unique characteristics made gold …
[HTML][HTML] Application of high-z gold nanoparticles in targeted cancer radiotherapy—Pharmacokinetic modeling, monte carlo simulation and radiobiological effect …
Simple Summary High-Z gold nanoparticles show potential as radiosensitizers in the
radiotherapy of cancer. In this paper, we introduce the benefits and procedures for the …
radiotherapy of cancer. In this paper, we introduce the benefits and procedures for the …
Investigation of the effects of cell model and subcellular location of gold nanoparticles on nuclear dose enhancement factors using Monte Carlo simulation
Purpose: The authors' aims were to model how various factors influence radiation dose
enhancement by gold nanoparticles (AuNPs) and to propose a new modeling approach to …
enhancement by gold nanoparticles (AuNPs) and to propose a new modeling approach to …
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