[HTML][HTML] The putative role of natural killer cells in patients with hepatitis C virus-related hepatocellular carcinoma

MM Hassona, EM Radwan… - Asian Pacific Journal …, 2021 - ncbi.nlm.nih.gov
Background: Natural Killer (NK) cells have crucial roles in immune responses against
malignant transformation including hepatocellular carcinoma (HCC). The NKG2D receptor …

Activity of IL-12/15/18 primed natural killer cells against hepatocellular carcinoma

L Zhuang, RJ Fulton, P Rettman, AE Sayan… - Hepatology …, 2019 - Springer
Background Hepatocellular carcinoma (HCC) is common, but remains difficult to treat.
Natural killer (NK) cells are cells of the innate immune system that have potent anti-cancer …

[HTML][HTML] Natural killer cell expansion with autologous feeder layer and anti-CD3 antibody for immune cell therapy of hepatocellular carcinoma

F Hosseinzadeh, J Ai, S Ebrahimi-Barough… - Asian Pacific Journal …, 2019 - ncbi.nlm.nih.gov
Background: one of the promising approaches for treatment of some cancers is adoptive cell
therapy using natural killer (NK) cells. Various methods have been investigated for ex vivo …

[PDF][PDF] Frequency and implications of natural killer and natural killer T cells in hepatocellular carcinoma

AM Zahran, AM Ashmawy, A Rayan, A Elkady… - Egypt J …, 2018 - researchgate.net
A complex role of the immune system has been highlighted in the development and
progression of hepatocellular carcinoma (HCC). Natural Killer cells (NK) and natural killer T …

KIR2DL3+ NKG2A− natural killer cells are associated with protection from productive hepatitis C virus infection in people who inject drugs

C Thoens, C Berger, M Trippler, H Siemann… - Journal of …, 2014 - Elsevier
Background & Aims Despite continuous high-risk behavior, a subgroup among people who
inject drugs (PWID) remains seronegative for hepatitis C virus (HCV) suggesting that a state …

High NKG2A expression contributes to NK cell exhaustion and predicts a poor prognosis of patients with liver cancer

C Sun, J Xu, Q Huang, M Huang, H Wen… - …, 2017 - Taylor & Francis
ABSTRACT Background and Aims: As the predominant lymphocyte subset in the liver,
natural killer (NK) cells have been shown to be highly associated with the outcomes of …

[HTML][HTML] Natural killer NKG2A and NKG2D in patients with colorectal cancer

GR Meckawy, AM Mohamed, WK Zaki… - Journal of …, 2019 - ncbi.nlm.nih.gov
Background Natural-killer group 2 (NKG2), a characteristic receptor of natural killer (NK) cell
family, assumes a vital role in modulating NK cytotoxic function. We aimed to detect mRNA …

Phenotypic characteristics of natural killer cells in acute hepatitis

H Cho - Journal of Microbiology, 2013 - Springer
Natural killer (NK) cells are the principal effector cell population in innate immune defense
against many types of infections. These cells are enriched in the liver, where they comprise …

Natural killer cell dysfunction in hepatocellular carcinoma and NK cell-based immunotherapy

C Sun, H Sun, W Xiao, C Zhang, Z Tian - Acta Pharmacologica Sinica, 2015 - nature.com
The mechanisms linking hepatitis B virus (HBV) and hepatitis C virus (HCV) infection to
hepatocellular carcinoma (HCC) remain largely unknown. Natural killer (NK) cells account …

NK cell receptor imbalance and NK cell dysfunction in HBV infection and hepatocellular carcinoma

C Sun, H Sun, C Zhang, Z Tian - Cellular & molecular immunology, 2015 - nature.com
Hepatocellular carcinoma (HCC) is currently the third leading cause of cancer mortality and
a common poor-prognosis malignancy due to postoperative recurrence and metastasis …