ADAMTS proteases in cardiovascular physiology and disease
S Santamaria, R de Groot - Open biology, 2020 - royalsocietypublishing.org
The a disintegrin-like and metalloproteinase with thrombospondin motif (ADAMTS) family
comprises 19 proteases that regulate the structure and function of extracellular proteins in …
comprises 19 proteases that regulate the structure and function of extracellular proteins in …
ADAMs family and relatives in cardiovascular physiology and pathology
A disintegrin and metalloproteinases (ADAMs) are a family of membrane-bound proteases.
ADAM-TSs (ADAMs with thrombospondin domains) are a close relative of ADAMs that are …
ADAM-TSs (ADAMs with thrombospondin domains) are a close relative of ADAMs that are …
ADAMTS proteases: key roles in atherosclerosis?
RC Salter, TG Ashlin, APL Kwan, DP Ramji - Journal of molecular …, 2010 - Springer
The ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) proteases
are secreted enzymes that regulate extracellular matrix turnover by degrading specific matrix …
are secreted enzymes that regulate extracellular matrix turnover by degrading specific matrix …
[HTML][HTML] ADAMTS proteases in vascular biology
JC Rodríguez-Manzaneque, R Fernández-Rodríguez… - Matrix Biology, 2015 - Elsevier
ADAMTS (a disintegrin and metalloprotease with thrombospondin motifs) proteases
comprise the most recently discovered branch of the extracellular metalloenzymes …
comprise the most recently discovered branch of the extracellular metalloenzymes …
The role of ADAMTS-4 in atherosclerosis and vessel wall abnormalities
Extracellular matrix proteins are regulated by metzincin proteases, like the disintegrin
metalloproteinases with thrombospondin motifs (ADAMTS) family members. This review …
metalloproteinases with thrombospondin motifs (ADAMTS) family members. This review …
Coronary disease association with ADAMTS7 is due to protease activity
T Mizoguchi, BT MacDonald, B Bhandary… - Circulation …, 2021 - Am Heart Assoc
Rationale: Despite contemporary therapy, coronary artery disease (CAD) remains a leading
cause of mortality. Genetic variants at ADAMTS7 have been associated with CAD and the …
cause of mortality. Genetic variants at ADAMTS7 have been associated with CAD and the …
A Disintegrin and Metalloproteinase (ADAM) and ADAM with thrombospondin motifs (ADAMTS) family in vascular biology and disease
S Zhong, RA Khalil - Biochemical pharmacology, 2019 - Elsevier
Abstract A Disintegrin and Metalloproteinase (ADAM) is a family of proteolytic enzymes that
possess sheddase function and regulate shedding of membrane-bound proteins, growth …
possess sheddase function and regulate shedding of membrane-bound proteins, growth …
ADAMTS-4 and-8 are inflammatory regulated enzymes expressed in macrophage-rich areas of human atherosclerotic plaques
D Wågsäter, H Björk, C Zhu, J Björkegren, G Valen… - Atherosclerosis, 2008 - Elsevier
OBJECTIVES: Remodeling of extracellular matrix (ECM) plays an important role in
inflammatory disorders such as atherosclerosis. ADAMTS (a disintegrin and …
inflammatory disorders such as atherosclerosis. ADAMTS (a disintegrin and …
Proteomic discovery of substrates of the cardiovascular protease ADAMTS7
A Colige, C Monseur, JTB Crawley… - Journal of Biological …, 2019 - ASBMB
The protease ADAMTS7 functions in the extracellular matrix (ECM) of the cardiovascular
system. However, its physiological substrate specificity and mechanism of regulation remain …
system. However, its physiological substrate specificity and mechanism of regulation remain …
A review of the ADAMTS family, pharmaceutical targets of the future
MD Tortorella, F Malfait, RA Barve… - Current …, 2009 - ingentaconnect.com
The a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family of
metalloproteases consists of 19 members. These enzymes play an important role in the …
metalloproteases consists of 19 members. These enzymes play an important role in the …