Osteoporosis is characterized by reduced bone formation and accumulation of adipocytes in
the bone marrow compartment. The decrease in bone mass results from an imbalance …

Epigenetics describes mechanisms which control gene expression and cellular processes
without changing the DNA sequence. The main mechanisms in epigenetics are DNA …

Osteoblasts and adipocytes share a common precursor in adult bone marrow and there is a
degree of plasticity between the two cell lineages. This has important implications for the …

Osteoporosis is a leading public health problem in our rapidly growing, aging population. It
is characterized by reduced bone mass and microarchitectural deterioration of bone tissue …

Bone is a specialized connective tissue with a calcified extracellular matrix in which cells are
embedded. Besides providing the internal support of the body and protection for vital …

Osteoporosis is a complex multifactorial disorder of the skeleton. Genetic factors are
important in determining peak bone mass and structure, as well as the predisposition to …

Osteoporosis is an age-related progressive bone disease. Recent advances in epigenetics,
cell biology, osteoimmunology, and genetic epidemiology have unraveled new mechanisms …

Osteoporosis is a complex multifactorial condition of the musculoskeletal system.
Osteoporosis and osteoporotic vertebral fracture (OVF) are associated with high medical …

Osteoporosis is one of the most prevalent skeletal system diseases; yet, its
pathophysiological mechanisms remain elusive. Adipocytes accumulate remarkably in the …

Osteoporosis is a condition where bone resorption exceeds bone formation leading to
degeneration. With an aging population, the prevalence of osteoporosis is on the rise …