The principles of Virchov's triad appear to be operational in atherothrombosis or arterial
thrombosis: local flow changes and particularly vacular wall damage are the main …

The blood coagulation system is a key survival mechanism that has developed to protect
man against lethal bleeding. A second function of blood coagulation is its close interaction …

Atherosclerosis is a disease recognized as the main cause of death in industrial countries.
The current paradigm establishes thrombosis to be the major reason for complications of …

The role of the hemostatic system in predisposing to or precipitating coronary heart disease
(CHD) represents an under-researched area. In the past decade developments in …

The obvious link between the coagulation system and atherosclerosis has long been
accepted in terms of thrombosis of a coronary artery, with the resultant myocardial infarction …

The pathogenesis of arterial thrombosis is complex and dynamic. Unlike venous thrombi,
arterial thrombi typically form under conditions of high blood flow and are mainly composed …

Several haemostatic factors have been associated with incident arterial cardiovascular
disease in prospective studies and meta-analyses. Plasma fibrinogen shows a strong and …

In 1856, Virchow published his now classic view of the factors that influence the
development of thrombosis (thrombogenesis)[1]. The three components needed for the …

An update of Virchow's triad for thrombogenesis can be considered by reference to
abnormalities in the endothelium/endocardium ('abnormal vessel wall'), abnormalities of …

Hemostatic factors play a crucial role in generating thrombotic plugs at sites of vascular
damage (atherothrombosis). However, whether hemostatic factors contribute directly or …