Ketamine is a cardiotoxic agent and can deplete ATP in cardiomyocytes through
mitochondrial dysfunction. We investigated the effects of gallic acid and sesame oil in …

This study investigated the effect of metyrosine against ketamine-induced cardiotoxicity in
rats and compared the results with the effect of metoprolol. In this study, rats were divided …

It is well known the use of ketamine and etomidate in clinical practice; however, the
difference in the systemic effects of these two anesthetic agents is still debatable. Thus, in …

Background: Mitochondria are the main target organelles through which drugs and
chemicals exert their toxic effect on cardiomyocytes. The mitochondria-related mechanisms …

Aim We aimed to investigate the preventive effects of carvacrol against ketamine-induced
cardiotoxicity biochemically and histopathologically in an experimental model. Material and …

Doxorubicin (DOX) is the most effective and frequently used anticancer drug but its
cardiotoxicity is the most important side effect that limits the clinical use of it. This study was …

Cardiac mitochondrial oxidative stress, calcium ion (Ca2+) overload and adenosine
triphosphate (ATP) depletion play an important role in the pathogenesis of myocardial …

Cardiac mitochondrial damage plays an important role in the pathology of myocardial
infarction. The protective effects of (−) epicatechin on cardiac mitochondrial damage in …

Arsenic trioxide (ATO) is a frontline chemotherapy drug used in the therapy of acute
promyelocytic leukemia. However, the clinical use of ATO is hindered by its cardiotoxicity …

Nicotine, the principal alkaloid in tobacco, induces a cellular damage on heart and
cardiomyocyte culture. We investigate the protective role of green tea extract (GTE) against …