Rationale & Objective Challenges in achieving valid risk prediction and stratification impede
treatment decisions and clinical research design for patients with glomerular diseases. This …

Rationale & Objective The use of kidney histopathology for predicting kidney failure is not
established. We hypothesized that the use of histopathologic features of kidney biopsy …

Background Few studies have evaluated whether histopathologic lesions on kidney biopsy
provide prognostic information beyond clinical and laboratory data. Methods We enrolled …

Background Biopsy-based studies on nephrosclerosis are lacking and the
clinicopathological predictors for progression of chronic kidney disease (CKD) are not well …

Background The chronic kidney disease (CKD) classification represents a simple tool to
evaluate kidney disease. However, it is not based on kidney histology and this might limit the …

Aims An important role of native kidney biopsy evaluation is to predict renal prognosis. We
aimed to develop a simplified chronicity score based solely on pathological features that are …

Background Semiquantitative visual inspection for glomerulosclerosis, interstitial fibrosis,
and arteriosclerosis is often used to assess chronic changes in native kidney biopsies …

Chronic changes represent an important component of native kidney biopsy evaluation and
have a major bearing on predicting prognosis and guiding treatment. We propose here a …

Background Global glomerulosclerosis is characteristic of chronic kidney disease and also
occurs with normal aging. Our goal was to determine the upper limit of normal for number of …

For nearly 7 decades kidney biopsies have been used in clinical practice to aid in diagnosis,
treatment, and prognosis for recovery or progression to kidney failure. The use of kidney …