Cryptococcus neoformans produces vesicles containing its major virulence factor, the
capsular polysaccharide glucuronoxylomannan (GXM). These vesicles cross the cell wall to …

Cryptococcus neoformans and distantly related fungal species release extracellular vesicles
that traverse the cell wall and contain a varied assortment of components, some of which …

Cryptococcus neoformans produces extracellular vesicles containing a variety of cargo,
including virulence factors. To become extracellular, these vesicles not only must be …

The cell wall of pathogenic fungi such as Cryptococcus neoformans, provides a formidable
barrier to secrete virulence factors that produce host cell damage. To study secretion of …

The mechanisms by which macromolecules are transported through the cell wall of fungi are
not known. A central question in the biology of Cryptococcus neoformans, the causative …

Cryptococcus neoformans, which causes fatal infection in immunocompromised individuals,
has an elaborate polysaccharide capsule surrounding its cell wall. The cryptococcal capsule …

Several genes are essential for Cryptococcus neoformans capsule synthesis, but their
functions are unknown. We examined the localization of glucuronoxylomannan (GXM) in …

The polysaccharidic capsule is the main virulence factor of Cryptococcus neoformans. It
primarily comprised of two polysaccharides: glucuronoxylomannan (GXM, 88% of the …

Many microbes are surrounded by phagocytosis‐inhibiting capsules. We took advantage of
the large size of the polysaccharide capsule of the pathogenic yeast Cryptococcus …

The human fungal pathogen Cryptococcus neoformans is characterized by its ability to
induce a distinct polysaccharide capsule in response to a number of host-specific …