Parenteral penicillin is the first-line regimen for treating syphilis. However, allergic reactions
and poor drug tolerance still present challenging problems with respect to use of this …

Penicillin is the gold standard for treating syphilis. However, allergic reactions, poor drug
tolerance and limited efficacy in patients remain a challenging problem. The objective of this …

Background Parenteral penicillin is the first-line regimen for treating syphilis, but unsuitable
for some patients due to penicillin allergy and lacking health resources. Unfortunately, the …

Background Penicillin's long-standing role as the reference standard in syphilis treatment
has led to global reliance. However, this dependence presents challenges, prompting the …

The World Health Organization estimates that at least 12 million people are infected with
syphilis in the world. Southeast Asia accounts for 5.8 million; Africa accounts for 3.5 million …

Background Syphilis is a complex systemic disease caused by a spirochete, Treponema
pallidum. The World Health Organization estimates that at least 12 million people worldwide …

Background The optimal antimicrobial regimen to treat syphilis in HIV-infected subjects
remains controversial. Objective To systematically assess the literature for studies …

Syphilis has challenged scientists and clinicians since its first appearance in the late 1400s
and debate continues to surround the best practice in management. Difficulties in defining …

Background The aim of this study was to assess the efficacy of ceftriaxone and benzathine
penicillin G (BPG) in nonpregnant, immunocompetent adults with early syphilis because …

Syphilis is a complex, cutaneous and multi-system disease caused by the spirochete
Treponema palladium. Syphilis is transmitted sexually, congenitally, and through blood …