Amanzio and Benedetti (J Neurosci 1999; 19: 484—494) first addressed the conditions
necessary for the activation of opioid and non-opioid placebo responses in human. Here, we …

Conditional responses in rodents such as locomotion have been reported for drugs of abuse
and similar to the placebo response in humans, may be associated with the expectation of …

We investigated the mechanisms underlying the activation of endogenous opioids in
placebo analgesia by using the model of human experimental ischemic arm pain. Different …

Placebo analgesia is one of the most robust and best-studied placebo effects. Recent
researches suggest that placebo analgesia activated the µ-opioid receptor signalling in the …

Analgesia is particularly susceptible to placebo responses. Recent studies in humans have
provided important insights into the neurobiology underlying placebo-induced analgesia …

Discovery of the involvement of endogenous opiates in placebo analgesia represents an
important step in understanding the mechanisms underlying placebo response. In the …

We suggest a new placebo analgesia animal model and investigated the role of the
dopamine and opioid systems in placebo analgesia. Before and after the conditioning, we …

Open-label placebos, or placebos without deception, have been found to induce analgesia,
a challenging concept that need to be investigated in detail. In particular, what we need to …

Recent research on human placebo analgesia has suggested the need for rodent models to
further elucidate the neural substrates of the placebo effect. This series of 3 experiments …

Placebo is a widespread phenomenon in medicine and biology and its mechanisms are
understood only partially. Most of our understanding of placebo comes from studies on pain …