Multiple sclerosis: Neuroimmune crosstalk and therapeutic targeting
M Charabati, MA Wheeler, HL Weiner, FJ Quintana - Cell, 2023 - cell.com
Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central
nervous system afflicting nearly three million individuals worldwide. Neuroimmune …
nervous system afflicting nearly three million individuals worldwide. Neuroimmune …
Toward the development of rational therapies in multiple sclerosis: what is on the horizon?
B Hemmer, HP Hartung - Annals of neurology, 2007 - Wiley Online Library
Although the cause of multiple sclerosis (MS) has remained obscure, many findings support
an autoimmune pathogenesis on the background of a complex interaction between multiple …
an autoimmune pathogenesis on the background of a complex interaction between multiple …
The immunology of multiple sclerosis
KE Attfield, LT Jensen, M Kaufmann… - Nature Reviews …, 2022 - nature.com
Our incomplete understanding of the causes and pathways involved in the onset and
progression of multiple sclerosis (MS) limits our ability to effectively treat this complex …
progression of multiple sclerosis (MS) limits our ability to effectively treat this complex …
[HTML][HTML] Multiple sclerosis: mechanisms and immunotherapy
C Baecher-Allan, BJ Kaskow, HL Weiner - Neuron, 2018 - cell.com
Multiple sclerosis (MS) is an autoimmune disease triggered by environmental factors that act
on a genetically susceptible host. It features three clinical stages: a pre-clinical stage …
on a genetically susceptible host. It features three clinical stages: a pre-clinical stage …
[HTML][HTML] Recent advances in understanding multiple sclerosis
Emerging data point to important contributions of both autoimmune inflammation and
progressive degeneration in the pathophysiology of multiple sclerosis (MS). Unfortunately …
progressive degeneration in the pathophysiology of multiple sclerosis (MS). Unfortunately …
The role of immune cells, glia and neurons in white and gray matter pathology in multiple sclerosis
G Mallucci, L Peruzzotti-Jametti, JD Bernstock… - Progress in …, 2015 - Elsevier
Multiple sclerosis is one of the most common causes of chronic neurological disability
beginning in early to middle adult life. Multiple sclerosis is idiopathic in nature, yet …
beginning in early to middle adult life. Multiple sclerosis is idiopathic in nature, yet …
Neuroprotection, regeneration and immunomodulation: broadening the therapeutic repertoire in multiple sclerosis
O Aktas, B Kieseier, HP Hartung - Trends in neurosciences, 2010 - cell.com
Multiple sclerosis (MS), an incurable but manageable disorder, is characterized by chronic
inflammatory demyelination and neurodegeneration in the central nervous system. Although …
inflammatory demyelination and neurodegeneration in the central nervous system. Although …
[HTML][HTML] Pre-clinical and clinical implications of “inside-out” vs.“outside-in” paradigms in multiple sclerosis etiopathogenesis
HE Titus, Y Chen, JR Podojil, AP Robinson… - Frontiers in cellular …, 2020 - frontiersin.org
Multiple Sclerosis (MS) is an immune-mediated neurological disorder, characterized by
central nervous system (CNS) inflammation, oligodendrocyte loss, demyelination, and …
central nervous system (CNS) inflammation, oligodendrocyte loss, demyelination, and …
The ins and outs of central nervous system inflammation—lessons learned from multiple sclerosis
V Ramaglia, O Rojas, I Naouar… - Annual review of …, 2021 - annualreviews.org
Multiple sclerosis (MS) is a chronic disease that is characterized by the inappropriate
invasion of lymphocytes and monocytes into the central nervous system (CNS), where they …
invasion of lymphocytes and monocytes into the central nervous system (CNS), where they …
The immune response in multiple sclerosis
S Rodríguez Murúa, MF Farez… - Annual Review of …, 2022 - annualreviews.org
Multiple sclerosis (MS) is a chronic autoimmune, inflammatory, and neurodegenerative
disease that affects the central nervous system (CNS). MS is characterized by immune …
disease that affects the central nervous system (CNS). MS is characterized by immune …