Recent advances in clinical diagnosis and pharmacotherapy options of membranous nephropathy

YN Wang, HY Feng, X Nie, YM Zhang, L Zou… - Frontiers in …, 2022 - frontiersin.org
Membranous nephropathy (MN) is the most common cause of nephrotic syndrome among
adults, which is the leading glomerular disease that recurs after kidney transplantation …

Mechanisms of primary membranous nephropathy

Y Gu, H Xu, D Tang - Biomolecules, 2021 - mdpi.com
Membranous nephropathy (MN) is an autoimmune disease of the kidney glomerulus and
one of the leading causes of nephrotic syndrome. The disease exhibits heterogenous …

Immune-monitoring disease activity in primary membranous nephropathy

P Cravedi, M Jarque, A Angeletti, À Favà… - Frontiers in …, 2019 - frontiersin.org
Primary membranous nephropathy (MN) is a glomerular disease mediated by autoreactive
antibodies, being the main cause of nephrotic syndrome among adult patients. While the …

Treatment of primary membranous nephropathy: where are we now?

A Angioi, N Lepori, AC López, S Sethi, FC Fervenza… - Journal of …, 2018 - Springer
In the last 10 years, basic science and clinical research have made important contributions
to the understanding and management of primary membranous nephropathy (MN). The …

Recent progress in deciphering the etiopathogenesis of primary membranous nephropathy

A Kronbichler, J Oh, B Meijers… - BioMed research …, 2017 - Wiley Online Library
Primary membranous nephropathy (MN) is the leading cause of nephrotic syndrome in
adults. Discovery of several antibodies has contributed to an increased understanding of …

[HTML][HTML] The role of PLA2R antibody in treatment of membranous nephropathy

K Dahan, V Gillion, C Johanet, H Debiec… - Kidney international …, 2018 - Elsevier
Membranous nephropathy (MN) is one of the leading causes of nephrotic syndrome in
adults. Some cases are associated with malignancy, infections, autoimmune systemic …

[HTML][HTML] Membranous nephropathy: integrating basic science into improved clinical management

DC Cattran, PE Brenchley - Kidney international, 2017 - Elsevier
Idiopathic membranous nephropathy (INM) remains a common cause of the nephrotic
syndrome in adults. The autoimmune nature of IMN was clearly delineated in 2009 with the …

Membranous nephropathy: new pathogenic mechanisms and their clinical implications

E Hoxha, L Reinhard, RAK Stahl - Nature Reviews Nephrology, 2022 - nature.com
Membranous nephropathy (MN) is characterized histomorphologically by the presence of
immune deposits in the subepithelial space of the glomerular filtration barrier; its clinical …

Perspectives in membranous nephropathy

NM Tomas, TB Huber, E Hoxha - Cell and Tissue Research, 2021 - Springer
The identification of the phospholipase A2 receptor 1 (PLA2R) and thrombospondin type-1
domain-containing protein 7A (THSD7A) as podocyte antigens in adult patients with …

Prognostic value of PLA2R autoimmunity detected by measurement of anti-PLA2R antibodies combined with detection of PLA2R antigen in membranous nephropathy …

F Pourcine, K Dahan, F Mihout, M Cachanado… - PloS one, 2017 - journals.plos.org
Introduction Clinical course of membranous nephropathy (MN) is difficult to predict.
Measurement of circulating anti-PLA2R autoantibodies (PLA2R-Ab) and detection in …