Urethral obstruction produces increased voiding frequency (0.7+/-0.06 to 1.1+/-0.08 h-1) and
hypertrophy of the urinary bladder (89+/-1.7 to 708+/-40 mg) with profound increments in the …

The case is compelling for the involvement of nerve growth factor (NGF) in the pathogenesis
of lower urinary tract disease, especially in conditions with altered neural function …

Spinal cord injury and cyclophosphamide-induced cystitis dramatically alter lower urinary
tract function and produce neurochemical, electrophysiological, and anatomical changes …

To gain insight into the effect of innervation on neurotrophin production, NGF levels in the
urinary bladder were measured following unilateral ganglionectomy (bladder denervation) …

Objective To measure the concentrations of nerve growth factor (NGF) in tissue biopsies
taken from subjects with a normal bladder and from patients diagnosed to have idiopathic …

Purpose: We investigated the effects of intrathecal application of nerve growth factor (NGF)
antibodies (Ab) on bladder hyperreflexia in chronic spinalized rats. Materials and Methods …

There is growing evidence that nerve growth factor may be an important mediator of the
sensory disorders associated with inflammation. This hypothesis was tested in a rat model of …

Of all isolated neurotrophic molecules Nerve Growth Factor (NGF) is the only one with a fully
established physiological function, at least in the peripheral nervous system (see Thoenen …

PURPOSE: Interstitial cystitis, a chronic disease of the bladder, is characterized by urinary
frequency, urgency and suprapubic pain. Nerve growth factor is a substance that may …

In situ hybridization using beta-nerve growth factor (NGF) DNA probes was used to
demonstrate NGF mRNA in spermatocytes and early spermatids of adult mouse. NGF mRNA …