Proteomic and functional profiles of a follicle‐stimulating hormone positive human nonfunctional pituitary adenoma

X Wang, T Guo, F Peng, Y Long, Y Mu, H Yang… - …, 2015 - Wiley Online Library
Nonfunctional pituitary adenoma (NFPA) is highly heterogeneous with different hormone‐
expressed subtypes in NFPA tissues including follicle‐stimulating hormone (FSH) positive …

Heterogeneity analysis of the proteomes in clinically nonfunctional pituitary adenomas

X Zhan, X Wang, Y Long, DM Desiderio - BMC medical genomics, 2014 - Springer
Background Clinically nonfunctional pituitary adenomas (NFPAs) without any clinical
elevation of hormone and with a difficulty in its early-stage diagnosis are highly …

TMT-based quantitative proteomics revealed follicle-stimulating hormone (FSH)-related molecular characterizations for potentially prognostic assessment and …

Y Wang, T Cheng, M Lu, Y Mu, B Li, X Li, X Zhan - EPMA Journal, 2019 - Springer
Background Non-functional pituitary adenoma (NFPA) is highly heterogeneous with different
hormone expression subtypes. Of them, follicle-stimulating hormone (FSH)-positive …

Identification of the proteomic variations of invasive relative to non‐invasive non‐functional pituitary adenomas

X Zhan, DM Desiderio, X Wang, X Zhan, T Guo… - …, 2014 - Wiley Online Library
The incomplete surgery section of invasive non‐functional pituitary adenomas (NFPA s)
carries the increased risks of complications and requires adjuvant radiotherapy and …

Quantitative analysis of proteome in non-functional pituitary adenomas: clinical relevance and potential benefits for the patients

T Cheng, Y Wang, M Lu, X Zhan, T Zhou, B Li… - Frontiers in …, 2019 - frontiersin.org
Background: Non-functional pituitary adenoma (NFPA) is a common tumor that occurs in the
pituitary gland, and generally without any symptoms at its early stage and without clinical …

[HTML][HTML] Two-dimensional gel electrophoresis coupled with mass spectrometry methods for an analysis of human pituitary adenoma tissue proteome

X Zhan, Y Huang, Y Long - Journal of Visualized Experiments …, 2018 - ncbi.nlm.nih.gov
Human pituitary adenoma (PA) is a common tumor that occurs in the human pituitary gland
in the hypothalamus-pituitary-targeted organ axis systems, and may be classified as either …

Exploration of molecular network variations in different subtypes of human non-functional pituitary adenomas

X Zhan, Y Long - Frontiers in Endocrinology, 2016 - frontiersin.org
Pituitary adenoma is a common disease occurring in pituitary that is a central regulatory
organ in endocrine system and is clinically categorized as functional and non-functional …

Integration of quantitative phosphoproteomics and transcriptomics revealed phosphorylation-mediated molecular events as useful tools for a potential patient …

D Liu, J Li, N Li, M Lu, S Wen, X Zhan - EPMA Journal, 2020 - Springer
Background Invasiveness is a very challenging clinical problem in nonfunctional pituitary
adenomas (NFPAs), and currently, there are no effective invasiveness-related molecular …

Human pituitary adenoma proteomics: new progresses and perspectives

X Zhan, X Wang, T Cheng - Frontiers in Endocrinology, 2016 - frontiersin.org
Pituitary adenoma (PA) is a common intracranial neoplasm that impacts on human health
through interfering hypothalamus–pituitary–target organ axis systems. The development of …

A reference map of a human pituitary adenoma proteome

X Zhan, DM Desiderio - Proteomics, 2003 - Wiley Online Library
In order to compare the proteomes from different cell types of pituitary adenomas for our long‐
term goal to clarify the molecular mechanisms that participate in the formation of pituitary …