HE 4 and CA 125 levels in the preoperative assessment of endometrial cancer patients: a prospective multicenter study (ENDOMET)

SL Antonsen, E Høgdall, IJ Christensen… - Acta obstetricia et …, 2013 - Wiley Online Library
Objective To evaluate whether human epididymis protein 4 (HE 4) and CA 125 correlate
with known high‐risk prognostic factors for endometrial cancer. Design Prospective …

Prognostic value of human epididymis protein 4 in endometrial cancer and its utility for surgical staging

L Minar, I Klabenesova, E Jandakova… - Journal of Obstetrics …, 2015 - Wiley Online Library
Aim An optimal surgical staging in the group of patients with the high‐risk type of
endometrial cancer is often limited by age and serious internal comorbidities. Therefore, in …

Predictive value of serum human epididymis protein 4 and cancer antigen 125 concentrations in endometrial carcinoma

SK Saarelainen, N Peltonen, T Lehtimäki… - American Journal of …, 2013 - Elsevier
Objective The purpose of this study was to evaluate the performance of preoperative serum
levels of human epididymis protein 4 (HE4) and cancer antigen 125 (CA125) in the …

HE4 is superior to CA125 in the detection of recurrent disease in high-risk endometrial cancer patients

K Abbink, PLM Zusterzeel, AJ Geurts-Moespot… - Tumor …, 2018 - journals.sagepub.com
Objective: To date, biomarkers are not routinely used in endometrial cancer diagnosis,
prognosis, and follow-up. The purpose of this study was to evaluate whether serum HE4 was …

Novel algorithm including CA-125, HE4 and body mass index in the diagnosis of endometrial cancer

T Knific, J Osredkar, Š Smrkolj, I Tonin, K Vouk… - Gynecologic …, 2017 - Elsevier
Objectives To evaluate the diagnostic and prognostic potential of preoperative serum CA-
125 and HE4 levels in patients with endometrial cancer. Methods Prospective case–control …

Utility of tumor marker HE4 as prognostic factor in endometrial cancer: a single-center controlled study

S Capriglione, F Plotti, A Miranda, R Ricciardi… - Tumor Biology, 2015 - Springer
This study aims to investigate the correlation between preoperative human epididymis
protein 4 (HE4) levels, endometrial cancer (EC) staging, and ideal cutoff for stage prediction …

Human epididymis protein 4 as a serum marker for diagnosis of endometrial carcinoma and prediction of clinical outcome

L Zanotti, E Bignotti, S Calza, E Bandiera… - Clinical Chemistry and …, 2012 - degruyter.com
Background: The purpose of this study was to assess the diagnostic and prognostic impact
of preoperative serum determination of human epididymis protein 4 (sHE4), and to …

Serum HE4 and CA125 combined to predict and monitor recurrence of type II endometrial carcinoma

Q Quan, Q Liao, W Yin, S Zhou, S Gong, X Mu - Scientific Reports, 2021 - nature.com
There is no recognized serum biomarker to predict the recurrence of endometrial carcinoma
(EC). We aimed to explore serum human epididymis protein 4 (HE4) and cancer antigen …

HE4 is an independent prognostic marker in endometrial cancer patients

I Mutz-Dehbalaie, D Egle, S Fessler, M Hubalek… - Gynecologic …, 2012 - Elsevier
OBJECTIVE: To evaluate the prognostic value of pretherapeutic serum HE4 in endometrial
cancer in comparison to CA125. METHODS: HE4 and CA125 serum levels were analyzed …

HE 4 tumor marker as a predictive factor for lymphatic metastasis in endometrial cancer

A Espiau Romera, T Cuesta Guardiola… - … of gynecology & …, 2020 - Wiley Online Library
Endometrial cancer is the most common genital cancer in high‐resource countries.
Treatment is essentially surgical, but the role of lymphadenectomy in the treatment of low …