Lipid alterations play a role in the integration of PD-1/PD-L1 inhibitors and anlotinib for the treatment of advanced non–small-cell lung cancer
L Liu, S Zhang, HY Yang, CH Zhou, Y Xiong… - Lipids in Health and …, 2024 - Springer
Background Studies have shown that integrating anlotinib with programmed death 1 (PD-
1)/programmed death-ligand 1 (PD-L1) inhibitors enhances survival rates among …
1)/programmed death-ligand 1 (PD-L1) inhibitors enhances survival rates among …
Levels of pretreatment blood lipids are prognostic factors in advanced NSCLC patients treated with anlotinib
M Tang, C Song, Y Zhang, X Xu, C Wang… - Lipids in Health and …, 2021 - Springer
Background Anlotinib, a small molecule for multi-target tyrosine kinase inhibition, is the third
or further line of defense for treatment of non-small cell lung cancer (NSCLC). Findings from …
or further line of defense for treatment of non-small cell lung cancer (NSCLC). Findings from …
Anlotinib affects systemic lipid metabolism and induces lipid accumulation in human lung cancer cells
Z Zhu, S Xu, J Ren, T Jiang, C Zhang, Z Yan - Lipids in Health and …, 2023 - Springer
Background Anlotinib has demonstrated encouraging clinical outcomes in the treatment of
lung cancer, soft tissue sarcoma and thyroid carcinoma. Several clinical studies have shown …
lung cancer, soft tissue sarcoma and thyroid carcinoma. Several clinical studies have shown …
Impact of weight loss on treatment with PD-1/PD-L1 inhibitors plus chemotherapy in advanced non-small-cell lung cancer
T Miyawaki, T Naito, M Yabe, H Kodama… - Supportive Care in …, 2022 - Springer
Purpose Programmed cell death-1 (PD-1)/programmed death-ligand 1 (PD-L1) inhibitors
plus chemotherapy have become the standard first line of treatment in patients with …
plus chemotherapy have become the standard first line of treatment in patients with …
Real-world outcomes for advanced non-small cell lung cancer patients treated with a PD-L1 inhibitor beyond progression
TE Stinchcombe, RA Miksad, A Gossai, SD Griffith… - Clinical Lung Cancer, 2020 - Elsevier
Background Clinical trials of anti-programmed cell death ligand 1 (PD-L1) inhibitor to treat
advanced non–small-cell lung cancer (aNSCLC) have permitted treatment beyond …
advanced non–small-cell lung cancer (aNSCLC) have permitted treatment beyond …
Very high PD‐L1 expression as a prognostic indicator of overall survival among patients with advanced non‐small cell lung cancer receiving anti‐PD‐(L) 1 …
Purpose Programmed death or ligand‐1 (PD‐(L) 1) pathway inhibitors confer improved
survival as the first‐line treatment for advanced non‐small cell lung cancer (aNSCLC) in …
survival as the first‐line treatment for advanced non‐small cell lung cancer (aNSCLC) in …
EGFR Mutations and ALK Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non–Small Cell Lung Cancer: A Retrospective …
Purpose: PD-1 inhibitors are established agents in the management of non–small cell lung
cancer (NSCLC); however, only a subset of patients derives clinical benefit. To determine …
cancer (NSCLC); however, only a subset of patients derives clinical benefit. To determine …
Tailoring Therapeutic Strategies in Non-Small-Cell Lung Cancer: The Role of Genetic Mutations and Programmed Death Ligand-1 Expression in Survival Outcomes
N Kobayashi, K Miura, A Kaneko, H Matsumoto… - Cancers, 2023 - mdpi.com
Simple Summary This study focuses on understanding the real-world impact of newly
introduced genetic tests and immune-based approaches on the survival of patients with non …
introduced genetic tests and immune-based approaches on the survival of patients with non …
Clinical impact of tumour burden on the efficacy of PD‐1/PD‐L1 inhibitors plus chemotherapy in non‐small‐cell lung cancer
T Miyawaki, H Kenmotsu, K Doshita… - Cancer …, 2023 - Wiley Online Library
Background Programmed cell death 1 (PD‐1)/programmed cell death ligand (PD‐L1)
inhibitors plus chemotherapy (ICI+ Chemo) is the standard treatment for advanced non …
inhibitors plus chemotherapy (ICI+ Chemo) is the standard treatment for advanced non …
Therapy line and associated predictors of response to PD-1/PD-L1-inhibitor monotherapy in advanced non-small-cell lung cancer: a retrospective Bi-centric cohort …
D Lang, F Huemer, G Rinnerthaler, A Horner, R Wass… - Targeted …, 2019 - Springer
Abstract Background Evidence on PD-1/PD-L1-directed immune checkpoint inhibitor (ICI)
therapy for advanced non-small-cell lung cancer (NSCLC) is mainly based on clinical trials …
therapy for advanced non-small-cell lung cancer (NSCLC) is mainly based on clinical trials …
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