Guanidinoacetic acid in human nutrition: Beyond creatine synthesis

SM Ostojic, J Jorga - Food Science & Nutrition, 2023 - Wiley Online Library
Guanidinoacetic acid (GAA) is a nutrient that has been used in human nutrition since the
early 1950s. Recommended for its role in creatine biosynthesis, GAA demonstrated …

Advanced physiological roles of guanidinoacetic acid

SM Ostojic - European journal of nutrition, 2015 - Springer
Dietary guanidinoacetic acid (GAA) seems to improve cellular bioenergetics by stimulating
creatine biosynthesis. However, GAA could have other biological functions that might affect …

Guanidinoacetic acid increases skeletal muscle creatine stores in healthy men

SM Ostojic, P Drid, J Ostojic - Nutrition, 2016 - search.proquest.com
Guanidinoacetic acid (GAA; also known as glycocyamine, betacyamine, or
guanidinoacetate) is an experimental dietary additive that enhances serum creatine …

Guanidinoacetic acid consumption via regular diet in adults

SM Ostojic, V Stajer, L Ratgeber, J Betlehem… - Annals of Nutrition and …, 2022 - karger.com
Guanidinoacetic acid (GAA; also known as glycocyamine) is a natural amino acid-like
derivative of glycine and L-arginine. GAA plays several metabolic roles in the human body …

[HTML][HTML] Safety of dietary guanidinoacetic acid: a villain of a good guy?

SM Ostojic - Nutrients, 2021 - mdpi.com
Guanidinoacetic acid (GAA) is a natural amino acid derivative that is well-recognized for its
central role in the biosynthesis of creatine, an essential compound involved in cellular …

[HTML][HTML] Guanidinoacetic acid as a novel food for skeletal muscle health

SM Ostojic, V Premusz, D Nagy, P Acs - Journal of Functional Foods, 2020 - Elsevier
Guanidinoacetic acid (GAA) is a direct endogenic precursor of creatine. GAA is also a re-
discovered nutraceutical that has been put forward as an energy-facilitating compound by …

Single-dose oral guanidinoacetic acid exhibits dose-dependent pharmacokinetics in healthy volunteers

SM Ostojic, A Vojvodic-Ostojic - Nutrition research, 2015 - Elsevier
Guanidinoacetic acid (GAA), the natural precursor of creatine, has potential as a dietary
supplement for human nutrition, yet no data are available regarding its dose-dependent …

Guanidinoacetic acid as a performance-enhancing agent

SM Ostojic - Amino acids, 2016 - Springer
Guanidinoacetic acid (GAA; also known as glycocyamine or guanidinoacetate) is the natural
precursor of creatine, and under investigation as a novel dietary agent. It was first identified …

Dose–response effects of oral guanidinoacetic acid on serum creatine, homocysteine and B vitamins levels

SM Ostojic, M Stojanovic, P Drid… - European journal of …, 2014 - Springer
Purpose Guanidinoacetic acid (GAA) is an intermediate in the biosynthesis of creatine (Cr),
yet its use in human nutrition is limited due to a lack of a clear understanding of its' dose …

Dietary guanidinoacetic acid increases brain creatine levels in healthy men

SM Ostojic, J Ostojic, P Drid, M Vranes, P Jovanov - Nutrition, 2017 - Elsevier
Objective Guanidinoacetic acid (GAA) is an experimental dietary additive that might act as a
creatine source in tissues with high-energy requirements. In this case study, we evaluated …