Melatonin was discovered to be a direct free radical scavenger less than 10 years ago.
Besides its ability to directly neutralize a number of free radicals and reactive oxygen and …

This review briefly summarizes the actions of melatonin in reducing molecular damage
caused by free radicals and associated oxygen-and nitrogenbased reactants. All the …

Melatonin, the chief secretory product of the pineal gland, was recently found to be a free
radical scavenger and antioxidant. This review briefly summarizes the published reports …

Melatonin is a potent endogenous free radical scavenger, actions that are independent of its
many receptor-mediated effects. In the last several years, hundreds of publications have …

This brief resume summarizes the evidence which shows that melatonin is a significant free
radical scavenger and antioxidant at both physiological and pharmacological concentrations …

Endogenously produced metabolites of ground state oxygen are highly reactive and
destructive to intracellular and extracellular molecules. The resulting damage, referred to as …

Abstract Melatonin (N-acetyl-5-methoxytryptamine), an endogenously produced indole
found throughout the animal kingdom, was recently reported, using a variety of techniques …

This review briefly summarizes the multiple actions by which melatonin reduces the
damaging effects of free radicals and reactive oxygen and nitrogen species. It is well …

The endogenous antioxidative defense system reduces molecular toxicity of oxygen and
nitrogen-based reactive species. Melatonin is an efficient direct and indirect antioxidant. It …

Publisher Summary N-Acetyl-5-methoxytryptamine (melatonin) was isolated from the
mammalian pineal gland. Its production in the pineal of all mammalian species is regulated …