The TGFbeta superfamily signaling pathway

A Weiss, L Attisano - Wiley Interdisciplinary Reviews …, 2013 - Wiley Online Library
The transforming growth factor (TGF) beta superfamily of secreted factors is comprised of
over 30 members including Activins, Nodals, Bone Morphogenetic Proteins (BMPs), and …

Signaling by the TGFβ superfamily

JL Wrana - Cold Spring Harbor perspectives in biology, 2013 - cshperspectives.cshlp.org
Signaling by the TGFβ Superfamily Cold Spring Harbor Perspectives in Biology Skip to main
page content HOME ABOUT SUBJECT COLLECTIONS ARCHIVE SUBSCRIBE ADVERTISE …

TGF-β signaling from receptors to Smads

A Hata, YG Chen - Cold Spring Harbor perspectives in …, 2016 - cshperspectives.cshlp.org
Transforming growth factor β (TGF-β) and related growth factors are secreted pleiotropic
factors that play critical roles in embryogenesis and adult tissue homeostasis by regulating …

TGF-β Signaling

K Tzavlaki, A Moustakas - Biomolecules, 2020 - mdpi.com
Transforming growth factor-β (TGF-β) represents an evolutionarily conserved family of
secreted polypeptide factors that regulate many aspects of physiological embryogenesis …

Negative regulation of TGF-β receptor/Smad signal transduction

S Itoh, P ten Dijke - Current opinion in cell biology, 2007 - Elsevier
Members of the transforming growth factor-β (TGF-β) family are highly conserved
multifunctional cell–cell signaling proteins that are of key importance for controlling …

TGFβ–SMAD signal transduction: molecular specificity and functional flexibility

B Schmierer, CS Hill - Nature reviews Molecular cell biology, 2007 - nature.com
Ligands of the transforming growth factor-β (TGFβ) superfamily of growth factors initiate
signal transduction through a bewildering complexity of ligand–receptor interactions …

Transforming growth factor-β receptors and Smads: regulatory complexity and functional versatility

EH Budi, D Duan, R Derynck - Trends in cell biology, 2017 - cell.com
Transforming growth factor (TGF)-β family proteins control cell physiology, proliferation, and
growth, and direct cell differentiation, thus playing key roles in normal development and …

The regulation of TGFβ signal transduction

A Moustakas, CH Heldin - Development, 2009 - journals.biologists.com
Transforming growth factor β (TGFβ) pathways are implicated in metazoan development,
adult homeostasis and disease. TGFβ ligands signal via receptor serine/threonine kinases …

Signal transduction by the TGF-β superfamily

L Attisano, JL Wrana - Science, 2002 - science.org
Transforming growth factor–β (TGF-β) superfamily members regulate a plethora of
developmental processes, and disruption of their activity has been implicated in a variety of …

Specificity, diversity, and regulation in TGF‐β superfamily signaling

E Piek, CH HELDIN, PTEN DIJKE - The FASEB Journal, 1999 - Wiley Online Library
Transforming growth factor‐β (TGF‐β) superfamily members are multifunctional cell‐cell
signaling proteins that play pivotal roles in tissue homeostasis and development of …