Genome-wide association studies (GWAS) involve testing genetic variants across the
genomes of many individuals to identify genotype–phenotype associations. GWAS have …

Genome-wide association studies (GWAS) have rapidly become a standard method for
disease gene discovery. A substantial number of recent GWAS indicate that for most …

Genome-wide association studies (GWAS) test hundreds of thousands of genetic variants
across many genomes to find those statistically associated with a specific trait or disease …

Over the past 15 years, genome-wide association studies (GWASs) have generated a
wealth of new information. Larger samples sizes, refined phenotypes and higher-resolution …

Genome-wide association studies (GWASs) have been heralded as a major advance in
biomedical discovery, having identified~ 2,000 robust associations with complex diseases …

The advent of the first wave of genome-wide association studies (GWAS) provided a new
conceptual framework in the search for variants underlying common disorders: a massive …

Genome-wide association (GWA) studies use high-throughput genotyping technologies to
assay hundreds of thousands of single-nucleotide polymorphisms (SNPs) and relate them to …

Most common diseases and quantitative traits are heritable: determined in part by genetic
variation within the population. The inheritance is typically polygenic in that combined effects …

Genetic association studies have made a major contribution to our understanding of the
genetics of complex disorders over the last 10 years through genome-wide association …

Background The number of genome-wide association studies (GWAS) is growing rapidly
leading to the discovery and replication of many new disease loci. Combining results from …