Bacterial ferrous iron transport: the Feo system

CKY Lau, KD Krewulak, HJ Vogel - FEMS microbiology reviews, 2016 - academic.oup.com
To maintain iron homeostasis within the cell, bacteria have evolved various types of iron
acquisition systems. Ferric iron (Fe3+) is the dominant species in an oxygenated …

Toward a mechanistic understanding of Feo-mediated ferrous iron uptake

AE Sestok, RO Linkous, AT Smith - Metallomics, 2018 - academic.oup.com
Virtually all organisms require iron and have evolved to obtain this element in free or
chelated forms. Under anaerobic or low pH conditions commonly encountered by numerous …

Feo–transport of ferrous iron into bacteria

ML Cartron, S Maddocks, P Gillingham, CJ Craven… - Biometals, 2006 - Springer
Bacteria commonly utilise a unique type of transporter, called Feo, to specifically acquire the
ferrous (Fe 2+) form of iron from their environment. Enterobacterial Feo systems are …

FeoA and FeoC are essential components of the Vibrio cholerae ferrous iron uptake system, and FeoC interacts with FeoB

EA Weaver, EE Wyckoff, AR Mey, R Morrison… - Journal of …, 2013 - Am Soc Microbiol
The ferrous iron transport system Feo is widely distributed among bacterial species, yet its
physical structure and mechanism of iron transport are poorly understood. In Vibrio …

Recent insights into iron import by bacteria

V Braun, K Hantke - Current opinion in chemical biology, 2011 - Elsevier
Bacteria are confronted with a low availability of iron owing to its insolubility in the Fe3+ form
or its being bound to host proteins. The bacteria cope with the iron deficiency by using host …

Ferrous iron efflux systems in bacteria

H Pi, JD Helmann - Metallomics, 2017 - academic.oup.com
Bacteria require iron for growth, with only a few reported exceptions. In many environments,
iron is a limiting nutrient for growth and high affinity uptake systems play a central role in iron …

Is the bacterial ferrous iron transporter FeoB a living fossil?

K Hantke - Trends in microbiology, 2003 - cell.com
The cytoplasmic membrane protein FeoB of Escherichia coli, Helicobacter pylori, Legionella
pneumophila and Synechocystis sp. strain PCC 6803 is necessary for Fe 2+ uptake. The C …

Bacterial iron homeostasis

SC Andrews, AK Robinson… - FEMS microbiology …, 2003 - academic.oup.com
Iron is essential to virtually all organisms, but poses problems of toxicity and poor solubility.
Bacteria have evolved various mechanisms to counter the problems imposed by their iron …

Iron uptake mechanisms of pathogenic bacteria

KG Wooldridge, PH Williams - FEMS microbiology reviews, 1993 - academic.oup.com
Most of the iron in a mammalian body is complexed with various proteins. Moreover, in
response to infection, iron availability is reduced in both extracellular and intracellular …

The FeoA protein is necessary for the FeoB transporter to import ferrous iron

H Kim, H Lee, D Shin - Biochemical and biophysical research …, 2012 - Elsevier
In many bacterial feo loci, the feoA gene is associated with the feoB gene. While the feoB-
encoded FeoB protein has been demonstrated as a ferrous iron [Fe (II)] transporter, the …