The specific retention of intravenously administered hemopoietic cells within bone marrow is
a complex multistep process. Despite recent insights, the molecular mechanics governing …

The nature and exact function of selectin ligands involved in hematopoietic progenitor cell
(HPC) homing to the bone marrow (BM) are unclear. Using murine progenitor homing …

The adhesive mechanisms allowing hematopoietic progenitor cells (HPC) homing to the
bone marrow (BM) after BM transplantation are poorly understood. We investigated the role …

Despite the wide use of mobilized peripheral blood (PB) progenitor cells (PBPC) for clinical
transplantation the mechanism (s) underlying their mobilization and subsequent engraftment …

OBJECTIVE: Hematopoietic stem cell homing and engraftment is dramatically altered by
cytokine exposure. These studies address the molecular mechanisms responsible for the …

Several components of the essential process of stem cell homing have now been
characterized. Cell adhesion molecules and their ligands, extracellular matrix components …

Adhesion molecules play a role in the migration of hematopoietic progenitor cells and
regulation of hematopoiesis. To study whether the mobilization process is associated with …

The conditions that control the migratory status of hematopoietic progenitor cells on
extracellular matrix (ECM) and that decide whether a cell migrates or adheres are …

Hematopoiesis is the best-studied stem cell system; the progenitor hierarchy has been
defined along with the cytokine requirements and transcriptional regulators. The …

Efficient bone marrow (BM) homing is a prerequisite for successful engraftment of
transplanted hematopoietic cells (HPCs). Contradictory conclusions about the contribution of …