Microspheres and nonspherical particles for embolization

A Laurent - Techniques in vascular and interventional radiology, 2007 - Elsevier
Last years, calibrated microspheres have proven their superiority in targeting embolization
over non spherical particles in many applications. For the very near future they represent the …

Development of “imageable” beads for transcatheter embolotherapy

KV Sharma, MR Dreher, Y Tang, W Pritchard… - Journal of Vascular and …, 2010 - Elsevier
PURPOSE: To develop and characterize radiopaque embolization microspheres capable of
in vivo detection with intraprocedural fluoroscopy and computed tomography (CT) imaging …

Preparation of radiopaque drug-eluting beads for transcatheter chemoembolization

CG Johnson, Y Tang, A Beck, MR Dreher… - Journal of Vascular and …, 2016 - Elsevier
Purpose To develop a simple method to produce radiopaque drug-eluting microspheres
(drug-eluting beads [DEBs]) that could be incorporated into the current clinical transcatheter …

New intrinsically radiopaque hydrophilic microspheres for embolization: synthesis and characterization

CSJ van Hooy-Corstjens, K Saralidze… - …, 2008 - ACS Publications
Polymeric particles currently used for embolization procedures have the disadvantage that
they are radiolucent, that is, invisible on X-ray images, and consequently the interventional …

Comparative study of chemoembolization loadable beads: in vitro drug release and physical properties of DC bead and hepasphere loaded with doxorubicin and …

O Jordan, A Denys, T De Baere, N Boulens… - Journal of vascular and …, 2010 - Elsevier
PURPOSE: To characterize in vitro the loadability, physical properties, and release of
irinotecan and doxorubicin from two commercially available embolization microspheres …

Review of the development of methods for characterization of microspheres for use in embolotherapy: Translating bench to cathlab

M Caine, D Carugo, X Zhang, M Hill… - Advanced …, 2017 - Wiley Online Library
Therapeutic embolotherapy is the deliberate occlusion of a blood vessel within the body,
which can be for the prevention of internal bleeding, stemming of flow through an …

First multimodal embolization particles visible on x-ray/computed tomography and magnetic resonance imaging

SH Bartling, J Budjan, H Aviv, S Haneder… - Investigative …, 2011 - journals.lww.com
Objectives: Embolization therapy is gaining importance in the treatment of malignant lesions,
and even more in benign lesions. Current embolization materials are not visible in imaging …

New acrylic microspheres for arterial embolization: combining radiopacity for precise localization with immobilized thrombin to trigger local blood coagulation

K Saralidze, CSJ van Hooy-Corstjens, LH Koole… - Biomaterials, 2007 - Elsevier
Particles currently used in arterial embolization therapy have several disadvantages, most
importantly their radiolucency. This means the radiologist cannot precisely asses the fate of …

DC bead: in vitro characterization of a drug-delivery device for transarterial chemoembolization

AL Lewis, MV Gonzalez, AW Lloyd, B Hall… - Journal of vascular and …, 2006 - Elsevier
PURPOSE: The purpose of this investigation is to present the in vitro characterization and
detailed drug-loading procedure for DC Bead, a microsphere product that can be loaded …

Evaluation of tris-acryl gelatin microsphere embolization with monochromatic X rays: comparison with polyvinyl alcohol particles

A Yamamoto, S Imai, M Kobatake, T Yamashita… - Journal of vascular and …, 2006 - Elsevier
PURPOSE: Imaging of blood vessels 30 μm or smaller can be achieved with use of
monochromatic x rays. The purpose of the present investigation was to use this method to …