The aim was to update the 2009 European League against Rheumatism (EULAR)
recommendations for the treatment of systemic sclerosis (SSc), with attention to new …

Purpose: The optimal treatment of systemic sclerosis (SSc) is a challenge because the
pathogenesis of SSc is unclear and it is an uncommon and clinically heterogeneous disease …

Systemic sclerosis has the highest case-specific mortality of any of the auto-immune
rheumatic diseases, as well as causing major morbidity. It is a major clinical challenge and …

Early diagnosis of systemic sclerosis (SSc) may allow the start of treatment that could slow
disease progression. For this reason early diagnosis of the disease is of pivotal importance …

Objectives Systemic sclerosis (SSc) is a rare disease requiring multicentre collaboration to
reveal comprehensive details of disease-related causes for morbidity and mortality. Methods …

OBJECTIVE To investigate the existence of differences among European referral centres for
systemic sclerosis (SSc) in the pattern of attendance and referral and in the clinical and …

Systemic sclerosis (SSc), also known as scleroderma, is a complex, multisystem disease
that results in severe morbidity, disability, and life-threatening complications. The wide range …

Objective There is a lack of agreement regarding treatment for many aspects of systemic
sclerosis (SS c). We undertook this study to generate SS c treatment algorithms endorsed by …

Objective. To develop guidelines for therapeutic trials designed to improve the overall
course of systemic sclerosis (SSc), that is, to reduce the development of significant organ …

Objective: To develop a provisional core set of response measures for clinical trials of
systemic sclerosis (SSc). Methods: The Scleroderma Clinical Trials Consortium (SCTC) …