Integrins are adhesion receptors that allow cells to sense and respond to
microenvironmental signals encoded by the extracellular matrix. They are crucial for the …

Integrin-mediated adhesion to the extracellular matrix plays an important role in regulating
cell survival and proliferation. There is now increasing evidence that integrins activate …

Integrins contribute to cell growth by providing a physical linkage between cytoskeletal
structures and the extracellular matrix, and also by participating in various signal …

All cellular processes are determined by adhesive interactions between cells and their local
microenvironment. Integrins, which constitute one class of cell-adhesion receptor, are …

Integrins are heterodimeric cell surface receptors composed of α and β subunits that control
adhesion, proliferation and gene expression. The integrin heterodimer binding to ligand …

Integrins are a family of adhesion receptors used by cells to interact with their extracellular
matrix. Integrins also function as signaling receptors, integrating information from the …

Integrins are the adhesion molecules and transmembrane receptors that consist of α and β
subunits. After binding to extracellular matrix components, integrins trigger intracellular …

Interactions between cancer cells and their surroundings can trigger essential signaling
cues that determine cell fate and influence the evolution of the malignant phenotype. As the …

Interactions with the extracellular matrix (ECM) provide cells with physical and chemical
cues that act in concert with growth factors to support survival and proliferation …

Integrins are adhesion receptors that connect cells to components of the extracellular matrix
or to counter receptors on other cells. Besides mediating stable adhesion, these receptors …