[HTML][HTML] The role of RNA m5C modification in cancer metastasis

Q Zhang, F Liu, W Chen, H Miao, H Liang… - … journal of biological …, 2021 - ncbi.nlm.nih.gov
Epigenetic modification plays a crucial regulatory role in the biological processes of
eukaryotic cells. The recent characterization of DNA and RNA methylation is still ongoing …

[HTML][HTML] The biological function of m6A reader YTHDF2 and its role in human disease

J Wang, A Lu - Cancer cell international, 2021 - Springer
Abstract N6-methyladenosine (m6A) modification is a dynamic and reversible post-
transcriptional modification and the most prevalent internal RNA modification in eukaryotic …

Dynamic transcriptomic m5C and its regulatory role in RNA processing

YS Chen, WL Yang, YL Zhao… - Wiley Interdisciplinary …, 2021 - Wiley Online Library
Abstract RNA 5‐methylcytosine (m5C) is a prevalent RNA modification in multiple RNA
species, including messenger RNAs (mRNAs), transfer RNAs (tRNAs), ribosomal RNAs …

[HTML][HTML] Main N6-methyladenosine readers: YTH family proteins in cancers

XY Dai, L Shi, Z Li, HY Yang, JF Wei, Q Ding - Frontiers in Oncology, 2021 - frontiersin.org
Among the over 150 RNA modifications, N6-methyladenosine (m6A) is the most abundant
internal modification in eukaryotic RNAs, not only in messenger RNAs, but also in …

[HTML][HTML] Insight into the structure, physiological function, and role in cancer of m6A readers—YTH domain-containing proteins

J Liao, Y Wei, J Liang, J Wen, X Chen, B Zhang… - Cell death …, 2022 - nature.com
Abstract YT521-B homology (YTH) domain-containing proteins (YTHDF1-3, YTHDC1-2) are
the most crucial part of N6-methyladenosine (m6A) readers and play a regulatory role in …

[HTML][HTML] Functions of N6-methyladenosine and its role in cancer

L He, H Li, A Wu, Y Peng, G Shu, G Yin - Molecular cancer, 2019 - Springer
Abstract N6-methyladenosine (m6A) is methylation that occurs in the N6-position of
adenosine, which is the most prevalent internal modification on eukaryotic mRNA …

[HTML][HTML] 5-methylcytosine RNA methyltransferases and their potential roles in cancer

M Li, Z Tao, Y Zhao, L Li, J Zheng, Z Li… - Journal of translational …, 2022 - Springer
Abstract In recent years, 5-methylcytosine (m5C) RNA modification has emerged as a key
player in regulating RNA metabolism and function through coding as well as non-coding …

[HTML][HTML] The potential role of RNA N6-methyladenosine in Cancer progression

T Wang, S Kong, M Tao, S Ju - Molecular cancer, 2020 - Springer
Abstract N6-methyladenosine (m6A) is considered the most common, abundant, and
conserved internal transcript modification, especially in eukaryotic messenger RNA (mRNA) …

[HTML][HTML] YTH Domain Proteins: A Family of m6A Readers in Cancer Progression

Y Xu, W Zhang, F Shen, X Yang, H Liu, S Dai… - Frontiers in …, 2021 - frontiersin.org
N 6-methyladenosine (m 6 A) is the most abundant internal modification in eukaryotic
messenger RNAs (mRNAs). m6A RNA methylation is involved in all stages of RNA life cycle …

[HTML][HTML] Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer

Y Nishizawa, M Konno, A Asai, J Koseki, K Kawamoto… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Recent studies that have emerged on the diversity of RNA modification in tumors suggest
their eligibility as bona fide targets in diagnosis and drug discovery. N6-methyladenosine (m …