Chronic pain, opioid prescriptions, and mortality in Denmark: a population-based cohort study

O Ekholm, GP Kurita, J Højsted, K Juel, P Sjøgren - PAIN®, 2014 - Elsevier
This study aimed to investigate the risk of death, development of cancer, and hospital
inpatient admissions resulting from injuries and toxicity/poisoning among opioid users with …

Burden of disease is often aggravated by opioid treatment of chronic pain patients: Etiology and prevention

H Breivik, A Stubhaug - Pain, 2014 - journals.lww.com
For more than two decades, Danish doctors have prescribed opioids for chronic noncancer
pain more liberally than have doctors in the neighboring countries. We have been looking to …

The epidemiology of regular opioid use and its association with mortality: Prospective cohort study of 466 486 UK biobank participants

GJ Macfarlane, M Beasley, GT Jones… - EClinicalMedicine, 2020 - thelancet.com
Background Opioids have, at most, small benefits for non-cancer pain in the medium and
long-term but there is good evidence that they cause harm. The current study describes the …

Chronic pain and use of opioids: a population-based pharmacoepidemiological study from the Norwegian prescription database and the Nord-Trøndelag health study

OMS Fredheim, M Mahic, S Skurtveit, O Dale… - PAIN®, 2014 - Elsevier
In previous studies on prescription patterns of opioids, accurate data on pain are missing,
and previous epidemiological studies of pain lack accurate data on opioid use. The present …

Opioid trends in Finland: a register-based nationwide follow-up study

J Keto, T Heiskanen, K Hamunen, ML Kalliomäki… - Scientific Reports, 2022 - nature.com
The opioid epidemic in the US has gotten payers, prescribers, and policymakers alike
interested in trends in opioid use. Despite no recognized opioid crisis in Europe, several …

Addictive behaviors related to opioid use for chronic pain: a population-based study

J Højsted, O Ekholm, GP Kurita, K Juel, P Sjøgren - PAIN®, 2013 - Elsevier
The growing body of research showing increased opioid use in patients with chronic pain
coupled with concerns regarding addiction encouraged the development of this population …

Increasing use of opioids from 2004 to 2007–pharmacoepidemiological data from a complete national prescription database in Norway

OMS Fredheim, S Skurtveit, H Breivik… - European Journal of …, 2010 - Elsevier
BACKGROUND: A high opioid consumption for cancer related and acute pain may indicate
adequate pain treatment. Analysis of a national, compulsory and complete database of all …

[HTML][HTML] Use of opioids in a Danish population-based cohort of cancer patients

L Jarlbaek, M Andersen, J Hallas, G Engholm… - Journal of pain and …, 2005 - Elsevier
Until recently, Denmark has had the highest use of strong opioids per capita in the world.
Our aim was to analyze cancer patients' use of opioids in this population by linkage between …

Deaths from opioid overdosing: implications of coroners' inquest reports 2008–2012 and annual rise in opioid prescription rates: a population-based cohort study

EE Shipton, AJ Shipton, JA Williman, EA Shipton - Pain and Therapy, 2017 - Springer
Introduction In the late 1990s multiple physicians and advocacy organizations promoted
increased use of opioids for the treatment of acute, chronic and cancer pain. There has been …

Critical issues on opioids in chronic non-cancer pain:: An epidemiological study

J Eriksen, P Sjøgren, E Bruera, O Ekholm… - Pain, 2006 - Elsevier
The aim of the study was epidemiologically to evaluate the long-term effects of opioids on
pain relief, quality of life and functional capacity in long-term/chronic non-cancer pain. The …