A group of novel trimethoxyphenyl (TMP)-based analogues were synthesized by varying the
azalactone ring of 2-(3, 4-dimethoxyphenyl)-4-(3, 4, 5-trimethoxybenzylidene) oxazolone 1 …

Based on the fact that 25-OCH3-PPD, a natural ginsengenin isolated from the leaves of
Panax ginseng, is a promising lead compound, novel 25-OCH3-PPD derivatives were …

To identify novel therapeutic agents to treat cancer, we synthesized a series of diaryl ether
derivatives. Structure–activity relationship studies revealed that the presence of a chlorine or …

A set of nine derivatives, including five brominated compounds, was synthesized and the
structures of these novel compounds were confirmed using 1H and 13C NMR as well as ESI …

A novel series of N-substituted-4-phenylphthalazin-1-ones 14a–g bearing different anilines
at the N-2 of phthalazin-1-one scaffold via acetyl-flexible linker was designed and …

A series of structurally new diheteroaryl thioether analogs was designed, prepared and
screened toward MGC-803, MKN-45, EC-109 and H1650. Most of the target compounds …

A series of novel 4β-[(5-substituted)-1, 2, 3, 4-tetrazolyl] podophyllotoxin derivatives were
synthesized by employing azide-nitrile click chemistry approach. All the derivatives were …

A series of novel benzimidazole-2-subsituted phenyl or pyridine propyl ketene derivatives
were designed and synthesized. The biological activities of these derivatives were then …

Abstract A series of 4β-[(4-alkyl)-1, 2, 3-triazol-1-yl] podophyllotoxin derivatives were
designed in silico, synthesised by employing click chemistry approach, and evaluated for …

Abstract A series of 5'-amino-2'-hydroxy-1, 3-diaryl-2-propen-1-ones (AC1-AC15) were
synthesized by Claisen-Schmidt condensation of 5'-acetamido-2'-hydroxy acetophenone …