A pharmacokinetic evaluation of oral edivoxetine hydrochloride for the treatment of attention deficit-hyperactivity disorder

JS Markowitz, BJ Brinda - Expert Opinion on Drug Metabolism & …, 2014 - Taylor & Francis
Introduction: The majority of available therapeutics to treat attention-deficit/hyperactivity
disorder (ADHD) are formulations of either methylphenidate or amphetamine. However …

Pharmacokinetics and pharmacodynamics of edivoxetine (LY2216684), a norepinephrine reuptake inhibitor, in pediatric patients with attention-deficit/hyperactivity …

W Kielbasa, T Quinlan, L Jin, W Xu… - Journal of Child and …, 2012 - liebertpub.com
Abstract Objective: Edivoxetine (LY2216684) is a selective and potent norepinephrine
reuptake inhibitor (NERI). The pharmacokinetics (PK) and pharmacodynamics (PD) of …

A randomized trial of edivoxetine in pediatric patients with attention-deficit/hyperactivity disorder

DY Lin, CJ Kratochvil, W Xu, L Jin… - Journal of Child and …, 2014 - liebertpub.com
Objective: The purpose of this study was to assess the efficacy and safety of edivoxetine
(LY2216684), a selective norepinephrine reuptake inhibitor, in pediatric patients with …

The effect of hepatic or renal impairment on the pharmacokinetics of edivoxetine, a selective norepinephrine transporter reuptake inhibitor

W Kielbasa, E Tesfaye, D Luffer-Atlas… - European journal of …, 2013 - Springer
Purpose To assess the impact of hepatic or renal impairment on the pharmacokinetics (PK)
of edivoxetine. Methods Two separate multi-center, open-label studies with males and …

Clinical outcomes from an open-label study of edivoxetine use in pediatric patients with attention-deficit/hyperactivity disorder

L Jin, W Xu, D Krefetz, D Gruener… - Journal of Child and …, 2013 - liebertpub.com
Objective: The purpose of this study was to assess the clinical outcomes from an open label
study of edivoxetine, a selective norepinephrine reuptake inhibitor, in pediatric patients with …

Long-term, open-label, safety study of edivoxetine monotherapy in children and adolescents with attention-deficit/hyperactivity disorder

ESM Nery, M Bangs, P Liu, J Ahl… - Journal of Child and …, 2017 - liebertpub.com
Objective: The purpose of this study was to assess the long-term safety and tolerability of
edivoxetine, a selective norepinephrine reuptake inhibitor, which was being developed as …

Lisdexamfetamine dimesylate: a new therapeutic option for attention-deficit hyperactivity disorder

C Steer, J Froelich, CA Soutullo, M Johnson, M Shaw - CNS drugs, 2012 - Springer
Attention-deficit hyperactivity disorder (ADHD) is associated with substantial functional,
clinical and economic burdens. It is among the most common psychiatric disorders in …

Stimulants and other non-stimulants for attention-deficit/hyperactivity disorder (ADHD)

JS Markowitz, G Yu - Applied clinical pharmacokinetics and …, 2016 - Springer
Methylphenidate, amphetamines, and atomoxetine are established agents used to treat
children, adolescents, and adults with attention-deficit/hyperactivity disorder (ADHD) …

[HTML][HTML] European, randomized, phase 3 study of lisdexamfetamine dimesylate in children and adolescents with attention-deficit/hyperactivity disorder

D Coghill, T Banaschewski, M Lecendreux… - European …, 2013 - Elsevier
This study evaluated the efficacy and safety of lisdexamfetamine dimesylate (LDX)
compared with placebo in children and adolescents with attention-deficit/hyperactivity …

Update on optimal use of lisdexamfetamine in the treatment of ADHD

V Madaan, V Kolli, DP Bestha… - … Disease and Treatment, 2013 - Taylor & Francis
Lisdexamfetamine (LDX) has been a recent addition to the treatment armamentarium for
Attention Deficit Hyperactivity Disorder (ADHD). It is unique among stimulants as it is a …