The effect of size, dose, and administration route on zein nanoparticle immunogenicity in BALB/c mice
F Li, Y Chen, S Liu, X Pan, Y Liu, H Zhao… - International journal …, 2019 - Taylor & Francis
Background Zein-based carriers are a promising delivery system for biomedical
applications. However, few studies involve systematic investigation on their in vivo …
applications. However, few studies involve systematic investigation on their in vivo …
Preparation of zein-based nanoparticles: Nanoprecipitation versus microfluidic-assisted manufacture, effects of PEGylation on nanoparticle characteristics and cellular …
J Meewan, S Somani, J Almowalad… - International Journal …, 2022 - Taylor & Francis
Background The manufacture of nanoparticles using manual methods is hampered by its
challenging scale-up and poor reproducibility. To overcome this issue, the production of zein …
challenging scale-up and poor reproducibility. To overcome this issue, the production of zein …
[HTML][HTML] PEG conjugated zein nanoparticles for in vivo use
C van Ballegooie, N Wretham, T Ren, IM Popescu… - Pharmaceutics, 2022 - mdpi.com
Zein can be utilized to form nanoscale particles for drug delivery applications. Despite the
ease of synthesis, these particles often aggregate when exposed to physiologically relevant …
ease of synthesis, these particles often aggregate when exposed to physiologically relevant …
Zein nanoparticles as vehicles for oral delivery purposes
JM Irache, CJ González-Navarro - Nanomedicine, 2017 - Taylor & Francis
Editorial Irache & González-Navarro proteins (eg, sodium caseinate)[12], polysaccharides
(eg, carboxymethyl chitosan)[8] or amino acids [11]. When orally administered, zein …
(eg, carboxymethyl chitosan)[8] or amino acids [11]. When orally administered, zein …
Zein nanoparticles for drug delivery: Preparation methods and biological applications
LA de Almeida Campos, AFS Neto… - International Journal of …, 2023 - Elsevier
Zein, a vegetable protein extracted from corn (Zea mays L.), forms a gastro-resistant and
mucoadhesive polymer that is cheap and easy to obtain and facilitates the encapsulation of …
mucoadhesive polymer that is cheap and easy to obtain and facilitates the encapsulation of …
[HTML][HTML] Zein-based nanoparticles as oral carriers for insulin delivery
C Reboredo, CJ González-Navarro, AL Martínez-López… - Pharmaceutics, 2021 - mdpi.com
Zein, the major storage protein from corn, has a GRAS (Generally Regarded as Safe) status
and may be easily transformed into nanoparticles, offering significant payloads for protein …
and may be easily transformed into nanoparticles, offering significant payloads for protein …
[HTML][HTML] Zein-based nanoparticles: Preparation, characterization, and pharmaceutical application
G Liu, D An, J Li, S Deng - Frontiers in Pharmacology, 2023 - frontiersin.org
Zein, as one of the natural and GRAS proteins in plant, is renewable, nontoxic,
biocompatible and biodegradable. Over the past decade, many research efforts have been …
biocompatible and biodegradable. Over the past decade, many research efforts have been …
Influence of formulation factors on the preparation of zein nanoparticles
S Podaralla, O Perumal - Aaps Pharmscitech, 2012 - Springer
The main objective of the present study was to investigate the influence of various
formulation parameters on the preparation of zein nanoparticles. 6, 7-dihydroxycoumarin …
formulation parameters on the preparation of zein nanoparticles. 6, 7-dihydroxycoumarin …
Zein-based nanoparticles for the oral delivery of insulin
L Inchaurraga, AL Martínez-López… - Drug Delivery and …, 2020 - Springer
The aim of this work was to evaluate oral nanocarriers, prepared from zein nanoparticles
coated with a poly (anhydride)-thiamine conjugate (GT), for the delivery of insulin …
coated with a poly (anhydride)-thiamine conjugate (GT), for the delivery of insulin …
The mechanisms of anti-PEG immune response are different in the spleen and the lymph nodes
P Grenier, V Chénard, N Bertrand - Journal of Controlled Release, 2023 - Elsevier
Polyethylene glycol (PEG) is a common ingredient in nanomedicines and pharmaceuticals.
Recent studies show that approximately 20–70% of humans have anti-PEG antibodies that …
Recent studies show that approximately 20–70% of humans have anti-PEG antibodies that …