[HTML][HTML] Effect of sub-chronic exposure to cigarette smoke, electronic cigarette and waterpipe on human lung epithelial barrier function

B Ghosh, H Reyes-Caballero, SG Akgün-Ölmez… - BMC pulmonary …, 2020 - Springer
Background Taking into consideration a recent surge of a lung injury condition associated
with electronic cigarette use, we devised an in vitro model of sub-chronic exposure of human …

Chronic inhalation of e-cigarette vapor containing nicotine disrupts airway barrier function and induces systemic inflammation and multiorgan fibrosis in mice

LE Crotty Alexander, CA Drummond… - American Journal …, 2018 - journals.physiology.org
Electronic (e)-cigarettes theoretically may be safer than conventional tobacco. However, our
prior studies demonstrated direct adverse effects of e-cigarette vapor (EV) on airway cells …

[HTML][HTML] Evaluation of E-cigarette liquid vapor and mainstream cigarette smoke after direct exposure of primary human bronchial epithelial cells

S Scheffler, H Dieken, O Krischenowski… - International journal of …, 2015 - mdpi.com
E-cigarettes are emerging products, often described as “reduced-risk” nicotine products or
alternatives to combustible cigarettes. Many smokers switch to e-cigarettes to quit or …

Comparison of cellular and transcriptomic effects between electronic cigarette vapor and cigarette smoke in human bronchial epithelial cells

S Anthérieu, A Garat, N Beauval, M Soyez, D Allorge… - Toxicology in vitro, 2017 - Elsevier
The use of electronic cigarette (e-cig) can be considered as an alternative to smoking.
However, due to a lack of thorough toxicological studies, absolute safety of these products …

Chronic electronic cigarette exposure in mice induces features of COPD in a nicotine-dependent manner

I Garcia-Arcos, P Geraghty, N Baumlin, M Campos… - Thorax, 2016 - thorax.bmj.com
Background The use of electronic (e)-cigarettes is increasing rapidly, but their lung health
effects are not established. Clinical studies examining the potential long-term impact of e …

[HTML][HTML] Electronic cigarette vapor exposure exaggerates the pro-inflammatory response during influenza A viral infection in human distal airway epithelium

N Schaunaman, T Crue, D Cervantes… - Archives of …, 2022 - Springer
Electronic cigarettes or vaping products have been marketed as a safer alternative to
smoking, but very little is known about the health effects in the human lung, particularly in the …

E-cigarettes induce toxicity comparable to tobacco cigarettes in airway epithelium from patients with COPD

HE O'Farrell, R Brown, Z Brown, B Miljevic… - Toxicology in Vitro, 2021 - Elsevier
Background The health effects of e-cigarettes in patients with pre-existing lung disease are
unknown. The aim of this study was to investigate whether aerosols from a fourth-generation …

Molecular impact of electronic cigarette aerosol exposure in human bronchial epithelium

E Moses, T Wang, S Corbett, GR Jackson… - Toxicological …, 2017 - academic.oup.com
Little evidence is available regarding the physiological effects of exposure to electronic
cigarette (ECIG) aerosol. We sought to determine the molecular impact of ECIG aerosol …

Acute exposure to electronic and combustible cigarette aerosols: effects in an animal model and in human alveolar cells

A Husari, A Shihadeh, S Talih, Y Hashem… - Nicotine & Tobacco …, 2016 - academic.oup.com
Background: Smoking electronic cigarettes (ECIG) is promoted as a safer alternative to
smoking combustible cigarettes. This study investigates the effects of ECIG aerosol and …

[HTML][HTML] Sub-ohm vaping increases the levels of carbonyls, is cytotoxic, and alters gene expression in human bronchial epithelial cells exposed at the air–liquid …

A Noël, E Hossain, Z Perveen, H Zaman, AL Penn - Respiratory research, 2020 - Springer
Background Exposure to electronic-cigarette (e-cig) aerosols induces potentially fatal e-cig
or vaping-associated lung injury (EVALI). The cellular and molecular mechanisms …