D3 dopamine receptor, behavioral sensitization, and psychosis
NM Richtand, SC Woods, SP Berger… - … & Biobehavioral Reviews, 2001 - Elsevier
Behavioral sensitization is a progressive, enduring enhancement of behaviors that develops
following repeated stimulant administration. It is mediated in part by dopaminergic pathways …
following repeated stimulant administration. It is mediated in part by dopaminergic pathways …
Role of dopamine D1‐like receptors in methamphetamine locomotor responses of D2 receptor knockout mice
MA Kelly, MJ Low, M Rubinstein… - Genes, Brain and …, 2008 - Wiley Online Library
Behavioral sensitization to psychostimulants manifests as an increased locomotor response
with repeated administration. Dopamine systems are accepted to play a fundamental role in …
with repeated administration. Dopamine systems are accepted to play a fundamental role in …
The dopamine D3 receptor antagonist nafadotride inhibits development of locomotor sensitization to amphetamine
NM Richtand, AD Logue, JA Welge, J Perdiue… - Brain research, 2000 - Elsevier
Behavioral sensitization is a well-studied model of behavioral plasticity mediated at least in
part by dopaminergic systems believed to play an important role in several psychiatric …
part by dopaminergic systems believed to play an important role in several psychiatric …
Amphetamine‐sensitized animals show a marked increase in dopamine D2 high receptors occupied by endogenous dopamine, even in the absence of acute …
While a range of dopamine D2‐related behaviors are exaggerated in amphetamine‐
sensitized animals, studies of the dopamine D2 receptor have reported either no change or …
sensitized animals, studies of the dopamine D2 receptor have reported either no change or …
Behavioral sensitization, alternative splicing, and d3 dopamine receptor-mediated inhibitory function
NM Richtand - Neuropsychopharmacology, 2006 - nature.com
Behavioral sensitization, the progressive and enduring augmentation of certain behaviors
following repetitive drug use, alters rodent locomotion in a long-standing manner. The same …
following repetitive drug use, alters rodent locomotion in a long-standing manner. The same …
The dopamine D3 receptor and drug addiction
P Sokoloff, BL Foll, S Perachon, R Bordet, S Ridray… - Neurotoxicity …, 2001 - Springer
Hedonic and reinforcing properties of drugs of abuse are closely related to brain dopamine
neuron activity. All these drugs increase dopamine release in the shell of nucleus …
neuron activity. All these drugs increase dopamine release in the shell of nucleus …
Dopamine D4 receptor‐deficient mice, congenic on the C57BL/6J background, are hypersensitive to amphetamine
PJ Kruzich, KL Suchland, DK Grandy - Synapse, 2004 - Wiley Online Library
Mice lacking the dopamine D4 receptor subtype (D4R−/−) are supersensitive to
methamphetamine and cocaine. We sought to expand and refine earlier experiments …
methamphetamine and cocaine. We sought to expand and refine earlier experiments …
Relapse to cocaine-and heroin-seeking behavior mediated by dopamine D2 receptors is time-dependent and associated with behavioral sensitization
TJ De Vries, ANM Schoffelmeer, R Binnekade… - …, 2002 - nature.com
The sensitizing properties of drugs of abuse have been proposed to play an important role in
the persistence of drug seeking behavior. We decided to evaluate the temporal relationship …
the persistence of drug seeking behavior. We decided to evaluate the temporal relationship …
D-2 but not D-1 dopamine agonists produce augmented behavioral response in rats after subchronic treatment with methamphetamine or cocaine
H Ujike, K Akiyama, S Otsuki - Psychopharmacology, 1990 - Springer
A study was performed to examine behavioral response to a challenge of selective
dopamine D-1 and D-2 agonists in rats previously sensitized by subchronic administration of …
dopamine D-1 and D-2 agonists in rats previously sensitized by subchronic administration of …
Dual alteration of limbic dopamine D1 receptor‐mediated signalling and the Akt/GSK3 pathway in dopamine D3 receptor mutants during the development of …
PC Chen, CL Lao, JC Chen - Journal of neurochemistry, 2007 - Wiley Online Library
The central dopamine system plays significant roles in motor activity and drug‐induced
behavioural sensitization. Our goal was to determine the significance of dopamine D3 …
behavioural sensitization. Our goal was to determine the significance of dopamine D3 …