Skeletal muscle weakness occurs with aging and in females this is compounded by the loss
of estrogen with ovarian failure. Estrogen deficiency mediates decrements in muscle …

There is a growing body of information supporting the beneficial effects of estrogen and
estrogen-based hormone therapy (HT) on maintenance and enhancement of muscle mass …

Human menopause is widely associated with impaired skeletal muscle quality and
significant metabolic dysfunction. These observations pose significant challenges to the …

The loss of skeletal muscle strength occurs with age, but the reason why there are
differences in rates and magnitude of losses between females and males is not clear. Sex …

The aging-related motor handicap and the growing population of elderly citizens have
enormous socioeconomic effects on the modern healthcare system. The mechanisms …

As women enter menopause, the concentration of estrogen and other female hormones
declines. This hormonal decrease has been associated with a number of negative …

Estrogen has a dramatic effect on musculoskeletal function. Beyond the known relationship
between estrogen and bone, it directly affects the structure and function of other …

Skeletal muscle regeneration efficiency declines with age for both men and women. This
decline impacts on functional capabilities in the elderly and limits their ability to engage in …

With aging and other muscle wasting diseases, men and women undergo similar
pathological changes in skeletal muscle: increased inflammation, enhanced oxidative …

Endocrine regulation of the balance between skeletal muscle anabolism and catabolism has
been investigated extensively. Factors determining whether hormones exert anabolic or …