Answer questions and earn CME/CNE The concept of frailty has become increasingly
recognized as one of the most important issues in health care and health outcomes and is of …

Background Frailty is a state of vulnerability to poor resolution of homeostasis following a
stressor event, such as chemotherapy or cancer surgery. Better knowledge of the …

Traditionally used as a descriptive term, frailty is now a recognized medical syndrome
identifying individuals with decreased physiologic reserve. Frailty is characterized by …

Background Cancer is common in older adults, who often have concurrent frailty. Frailty is a
strong predictor of adverse outcomes in surgical patients. Our objective is to systematically …

There are over 15 million survivors of cancer in the United States whose rates of frailty, an
aging phenotype, range from just under 10% to over 80%. Frailty impacts not only disease …

Aging is associated with a progressive decline in the functional reserve of many organ
systems, 22 and this functional restriction can compromise the tolerance of stress, including …

Frailty, an age-related condition of increased vulnerability to acute endogenous or
exogenous stressors, is a key barrier to successful treatment of cancer in older people. In …

Background The majority of colorectal cancer is diagnosed in people aged> 65 years, yet
the elderly are less likely to undergo curative surgery. Chronological age is poorly correlated …

Importance Frailty based on the modified Frailty Index is associated with poor postoperative
outcomes. However, the index requires high levels of personnel time and effort and often …

Objective The aim of the present article was to discuss currently available evidence on the
impact of frailty assessment on adverse postoperative outcomes and survival in patients …