Corticosteroid-induced cataracts

RC Urban Jr, E Cotlier - Survey of ophthalmology, 1986 - Elsevier
The association linking corticosteroid therapy with the development of posterior subcapsular
cataracts has been well documented. These drugs are widely used therapeutically …

What causes steroid cataracts? A review of steroid‐induced posterior subcapsular cataracts

AI Jobling, RC Augusteyn - Clinical and experimental …, 2002 - Wiley Online Library
Prolonged use of glucocorticoids is a significant risk factor for the development of posterior
subcapsular cataract. This places restrictions on the use of glucocorticoids in the treatment …

Effect of corticosteroids on cataract formation

HW Skalka, JT Prchal - Archives of Ophthalmology, 1980 - jamanetwork.com
• While the cataractogenic effects of corticosteroids are beyond dispute, disagreement exists
concerning effects of total dose, intensity of dose, and duration of administration on cataract …

Use of inhaled corticosteroids and the risk of cataracts

RG Cumming, P Mitchell… - New England Journal of …, 1997 - Mass Medical Soc
Background The use of systemic corticosteroids is a risk factor for the development of
posterior subcapsular cataracts, but the association between inhaled corticosteroids and …

The etiology of steroid cataract

ER James - Journal of Ocular Pharmacology and Therapeutics, 2007 - liebertpub.com
Steroid-induced posterior subcapsular cataracts (PSCs) exhibit three main distinctive
characteristics:(i) association only with steroids possessing glucocorticoid activity,(ii) …

The association of cataract formation and systemic corticosteroid therapy

CL Giles, GL Mason, IF Duff, JA McLean - JAMA, 1962 - jamanetwork.com
A group of 56 patients who had received sustained, systemic corticosteroid therapy were
examined in order to determine the incidence of posterior subcapsular cataracts. Thirty-eight …

Use of inhaled and oral corticosteroids and the long-term risk of cataract

JJ Wang, E Rochtchina, AG Tan, RG Cumming… - Ophthalmology, 2009 - Elsevier
OBJECTIVE:: Longitudinal associations between inhaled and oral corticosteroid use and 10-
year incident cataract were examined. DESIGN: Population-based cohort study …

Posterior subcapsular cataracts induced by corticosteroids in patients with rheumatoid arthritis

RL Black, RB Oglesby, L von Sallmann, JJ Bunim - Jama, 1960 - jamanetwork.com
POSTERIOR subcapsular cataracts (PSC) are generally associated with exposure to toxic
agents, posterior intraocular disease, ionizing radiation, or blunt trauma. As a rule these …

Ocular complications of topical, peri-ocular, and systemic corticosteroids

MC Carnahan, DA Goldstein - Current opinion in ophthalmology, 2000 - journals.lww.com
Topical ophthalmic, oral, and intravenous corticosteroids have long been associated with
ocular side effects. Recent data suggest that inhaled corticosteroids are also associated with …

Nonenzymatic addition of glucocorticoids to lens proteins in steroid-induced cataracts.

S Manabe, R Bucala, A Cerami - The Journal of clinical …, 1984 - Am Soc Clin Investig
A frequent manifestation of long-term glucocorticoid administration is the occurrence of
posterior subcapsular cataracts. The molecular basis for this effect has not yet been …