[HTML][HTML] Tumor cell-induced platelet aggregation as an emerging therapeutic target for cancer therapy
W Strasenburg, J Jóźwicki, J Durślewicz… - Frontiers in …, 2022 - frontiersin.org
Tumor cells have the ability to induce platelet activation and aggregation. This has been
documented to be involved in tumor progression in several types of cancers, such as lung …
documented to be involved in tumor progression in several types of cancers, such as lung …
[HTML][HTML] Platelet cancer cell interplay as a new therapeutic target
K Morris, B Schnoor, AL Papa - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
The interaction between circulating tumor cells and platelets is a key factor in cancer
metastasis. These interactions, driven by a variety of receptors, support circulating tumor …
metastasis. These interactions, driven by a variety of receptors, support circulating tumor …
[HTML][HTML] Bidirectional interaction between cancer cells and platelets provides potential strategies for cancer therapies
L Yu, Y Guo, Z Chang, D Zhang, S Zhang, H Pei… - Frontiers in …, 2021 - frontiersin.org
Platelets are essential components in the tumor microenvironment. For decades, clinical
data have demonstrated that cancer patients have a high risk of thrombosis that is …
data have demonstrated that cancer patients have a high risk of thrombosis that is …
[HTML][HTML] Platelet-cancer interplay: molecular mechanisms and new therapeutic avenues
A Braun, HJ Anders, T Gudermann… - Frontiers in …, 2021 - frontiersin.org
Although platelets are critically involved in thrombosis and hemostasis, experimental and
clinical evidence indicate that platelets promote tumor progression and metastasis through a …
clinical evidence indicate that platelets promote tumor progression and metastasis through a …
Involvement of platelets in tumor cell metastasis
B Tesfamariam - Pharmacology & Therapeutics, 2016 - Elsevier
Extensive experimental evidence indicates that platelets contribute to tumor cell proliferation
and metastasis through direct interactions and secreted bioactive proteins. Activated …
and metastasis through direct interactions and secreted bioactive proteins. Activated …
[HTML][HTML] The critical role of platelet in cancer progression and metastasis
L Zhou, Z Zhang, Y Tian, Z Li, Z Liu, S Zhu - European Journal of Medical …, 2023 - Springer
Platelets play a crucial role in cancer blood metastasis. Various cancer-related factors such
as Toll-like receptors (TLRs), adenosine diphosphate (ADP) or extracellular matrix (ECM) …
as Toll-like receptors (TLRs), adenosine diphosphate (ADP) or extracellular matrix (ECM) …
Platelets in tumor progression: a host factor that offers multiple potential targets in the treatment of cancer
D Sharma, KE Brummel‐Ziedins… - Journal of cellular …, 2014 - Wiley Online Library
While platelets are well known to play a central role in hemostasis and thrombosis, there is
emerging experimental evidence to suggest that they also mediate tumor cell growth …
emerging experimental evidence to suggest that they also mediate tumor cell growth …
The role of platelet activation in tumor metastasis
L Borsig - Expert review of anticancer therapy, 2008 - Taylor & Francis
Platelets are highly reactive components of the circulatory system, which exert not only
haemostatic activity but also contribute to the modulation of various pathological conditions …
haemostatic activity but also contribute to the modulation of various pathological conditions …
Cancer and platelet crosstalk: opportunities and challenges for aspirin and other antiplatelet agents
Platelets have long been recognized as key players in hemostasis and thrombosis;
however, growing evidence suggests that they are also significantly involved in cancer, the …
however, growing evidence suggests that they are also significantly involved in cancer, the …
The dynamic role of platelets in cancer progression and their therapeutic implications
S Li, Z Lu, S Wu, T Chu, B Li, F Qi, Y Zhao… - Nature Reviews Cancer, 2024 - nature.com
Systemic antiplatelet treatment represents a promising option to improve the therapeutic
outcomes and therapeutic efficacy of chemotherapy and immunotherapy due to the critical …
outcomes and therapeutic efficacy of chemotherapy and immunotherapy due to the critical …