Uric acid (UA) is an end product of purine metabolism in humans and great apes. UA acts as
an antioxidant and it accounts for 50% of the total antioxidant capacity of biological fluids in …

The relationship between uric acid and cardiovascular disease has been known since the
19th century, after that many authors reported the classical association of gout …

Hyperuricaemia is common in subjects with cardiovascular disease, but is not commonly
considered a true risk factor. Recent studies suggest that uric acid is biologically active and …

Uric acid has long been associated with cardiovascular disease. Most epidemiological
evidence suggests a significant, graded, independent and specific association between the …

Uric acid (urate), an organic compound comprised of carbon, nitrogen, oxygen and
hydrogen, is the final oxidation product of purine catabolism in humans, higher primates and …

Hyperuricemia, which has been considered as a cause of gout and nephrolithiasis has
recently been suggested to be associated with hypertension, coronary heart disease, heart …

In recent years, serum uric acid (SUA) as a determinant of cardiovascular (CV) risk has
gained interest. Epidemiological, experimental and clinical data show that patients with …

This review summarizes recent published literature on the association between serum uric
acid and cardiovascular disease, a relationship which is complex and not fully elucidated …

Uric acid, the end-product of purine metabolism in humans, is not only a cause of gout, but
also may play roles in developing cardiovascular diseases such as hypertension, atrial …

The importance of serum uric acid as a risk factor for cardiovascular disease has been
debated for nearly 50 years. However, in recent months the debate has intensified as a …